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ProteomicsTRIM28 is an E3 ligase of IRP2 suppressing ischemia/reperfusion-induced myocardial ferroptosis
Myocardial ischemia/reperfusion (I/R) injury is a common and severe clinical complication in patients with ischemic heart disease (IHD) after reperfusion therapy. Effective therapeutic strategies for myocardial I/R injury remain limited. Ferroptosis is a form of regulated cell death characterized by...
ORGANISM(S): Rattus Norvegicus 
2025-12-28 | PXD072478 |
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
UnknownDiffusing capacity in chronic obstructive pulmonary disease assessment: A meta-analysis.
Not available
S-EPMC8649441 | biostudies-literature
UnknownDietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway.
Not available
S-EPMC8709963 | biostudies-literature
UnknownAge-specific prevalence, subtypes and risk factors of metabolic diseases in Chinese adults and the different patterns from other racial/ethnic populations.
Not available
S-EPMC9664823 | biostudies-literature
MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
UnknownSerpinG1: A Novel Biomarker Associated With Poor Coronary Collateral in Patients With Stable Coronary Disease and Chronic Total Occlusion.
Not available
S-EPMC9798810 | biostudies-literature
UnknownGene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
Not available
S-EPMC16901 | biostudies-literature
UnknownTubular epithelial C1orf54 mediates protection and recovery from acute kidney injury.
Not available
S-EPMC6156286 | biostudies-literature
GenomicsDNA demethylation by Tet dioxygenases controls gastrula patterning by regulating Lefty-Nodal signaling
Mammalian genomes are subjected to epigenetic modifications, including cytosine methylation by DNA methyltransferases (Dnmt) and further oxidation by Ten-eleven-translocation (Tet) family of dioxygenases. Cytosine methylation plays key roles in multiple processes such as genomic imprinting and X-chr...
ORGANISM(S): Mus musculus 
2016-10-27 | E-GEOD-76261 | biostudies-arrayexpress
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