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ProteomicsLactylation of nucleus pulposus cells
Nucleus pulposus (NP) resides in hypoxic microenvironment due to the avascular structure of intervertebral disc (IVD). Intracellular lactate drives lysine lactylation (Kla) as a newly epigenetic modification. However, the impact of Kla on NPCs remains unknown. Using liquid chromatography-tandem mass...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-06 | PXD048244 | Pride
Lactylation Nucleus pulposus cells Intervertebral disc degeneration 
UnknownHigh G2 and S-phase expressed 1 expression promotes acral melanoma progression and correlates with poor clinical prognosis.
Not available
S-EPMC5989838 | biostudies-literature
UnknownA spike-targeting bispecific T cell engager strategy provides dual layer protection against SARS-CoV-2 infection in vivo.
Not available
S-EPMC10234585 | biostudies-literature
UnknownBAX-mediated ammonia-driven cell death: a novel prognostic and therapeutic target in clear cell renal cell carcinoma.
Not available
S-EPMC12085854 | biostudies-literature
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
UnknownIdentification of key genes in the response to Salmonella enterica Enteritidis, Salmonella enterica Pullorum, and poly(I:C) in chicken spleen and caecum.
Not available
S-EPMC3950952 | biostudies-literature
UnknownPerfluorooctanoic acid exposure for 28 days affects glucose homeostasis and induces insulin hypersensitivity in mice.
Not available
S-EPMC4464286 | biostudies-literature
UnknownDehydroevodiamine suppresses inflammatory responses in adjuvant-induced arthritis rats and human fibroblast-like synoviocytes.
Not available
S-EPMC8805850 | biostudies-literature
UnknownDiscovery and Functional Analysis of Secondary Hair Follicle miRNAs during Annual Cashmere Growth.
Not available
S-EPMC9864137 | biostudies-literature
UnknownHuman glioma stem-like cells induce malignant transformation of bone marrow mesenchymal stem cells by activating TERT expression.
Not available
S-EPMC5732816 | biostudies-literature
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