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MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
MetabolomicsAltered Fecal Microbiome and Correlations of the Metabolome with Plasma Metabolites in Dairy Cows with Left Displaced Abomasum

Left displaced abomasum (LDA) in postpartum dairy cows contributes to significant economic losses. LDA is characterized by excessive lipolysis and insulin resistance. Although gut dysbiosis is implicated, little is known about the role of the gut microbiota in the abnormal metabolic processes of ...

2022-08-17 | MTBLS2441 | MetaboLights
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
MetabolomicsHost–gut microbiota–bile acid axis integrates dietary starch to regulate milk fatty acid metabolism in dairy goats

Bile acids (BA) and BA-related microbiota are essential for ruminant lipid metabolism, yet targeted modulation to enhance production and health remain underexplored. Herein, we investigated the interplay between dietary rumen degradable starch, BA metabolism, and milk fatty acids (FAs) synthesis...

2025-12-09 | MTBLS13483 | MetaboLights
MetabolomicsThe impact of rumen and hindgut microbiomes on the persistent productivity of dairy cows

Background

Persistent productivity and productive lifespan determine the lifetime output of dairy cows and influence overall herd profitability. The composition and metabolic activity of the gastrointestinal microbiota of dairy cows influence persistent productivity. However, the processes ...

2025-08-21 | MTBLS12870 | MetaboLights
MetabolomicsThe impact of rumen and hindgut microbiomes on the persistent productivity of dairy cows.

Background

Persistent productivity and productive lifespan determine the lifetime output of dairy cows and influence overall herd profitability. The composition and metabolic activity of the gastrointestinal microbiota of dairy cows influence persistent productivity. However,...

2025-08-22 | MTBLS12879 | MetaboLights
MetabolomicsPrevotella vs. Ruminococcus enterotypes drive divergent milk fat synthesis in dairy cows through rumen microbiota-host metabolic crosstalk

Background: High-yield dairy cows are usually accompanied with lower milk fat (MF) rate, with huge variations in MF contents among individuals. The potential mechanisms of key microorganisms, their genes and metabolites participate in MF synthesis are still not well understood. By selec...

2025-10-28 | MTBLS13211 | MetaboLights
MetabolomicsMulti-omics and intervention analyses reveal a hindgut microbiota–secondary bile acid–mammary axis linked to milk yield in dairy cows
Background In large scale dairy farming systems, maintaining stable milk yield post-lactation peak is crucial for dairy farms’ economic benefits. While sufficient evidence shows the microbiota profoundly impacts host production efficiency, the specific mechanisms by which hindgut microbiota support ...
2026-05-22 | MTBLS14549 | MetaboLights
MetabolomicsMulti-omics and intervention analyses reveal a hindgut microbiota–secondary bile acid–mammary axis linked to milk yield in dairy cows_Mus musculus_Serum

Background

In large scale dairy farming systems, maintaining stable milk yield post-lactation peak is crucial for dairy farms’ economic benefits. While sufficient evidence shows the microbiota profoundly impacts host production efficiency, the specific mechanisms by which hindgut microbiota...

2026-04-15 | MTBLS14063 | MetaboLights
MetabolomicsUnravelling the interaction between the phageome and bacteriome in the rumen and its role in influencing metabolome dynamics in dairy cows at different lactation stages

Background: Although the roles of rumen microbiome in milk yield and milk protein synthesis have been widely recognized, knowledge on how ruminal microbiome dynamic changes affect these two traits during the whole lactation is lacking. Phages have been shown to affect&nbs...

2025-08-11 | MTBLS12816 | MetaboLights
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