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MetabolomicsAn integrated genomic and metabolomic approach for defining survival time in adult oligodendrogliomas patients

INTRODUCTION: The identification of frequent acquired mutations shows that patients with oligodendrogliomas have divergent biology with differing prognoses regardless of histological classification. A better understanding of molecular features as well as their metabolic pathways...

2021-10-06 | MTBLS869 | MetaboLights
TranscriptomicsMolecular mechanisms underlying the metabolic changes induced by the Pro12Ala PPARγ2 variant in mice
The metabolic impact of the common peroxisome proliferator-activated receptor gamma isoform 2 (PPARγ2) variant Pro12Ala in human populations has been widely debated. We demonstrate using a Pro12Ala knock-in model that on chow Ala/Ala mice are leaner, have improved insulin sensitivity and plasma lip...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-13305 | biostudies-arrayexpress
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