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TranscriptomicsIntegrated pathways for neutrophil recruitment and inflammation in leprosy
Neutrophil recruitment is pivotal to host defense against microbial infection, but also contributes to the immunopathology of disease. We investigated the mechanism of neutrophil recruitment in human infectious disease by bioinformatic pathways analysis of the gene expression profiles in the skin l...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-GEOD-16844 | biostudies-arrayexpress
UnknownInterferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.
Not available
S-EPMC6420824 | biostudies-literature
TranscriptomicsExpression data from Saccharomyces cerevisiae treated with Small Molecule Enhancers of Rapamycin (SMERs)
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-29 | E-GEOD-22269 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae Met30 temperature-sensitive strain
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2011-06-30 | E-GEOD-22270 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae temperature-sensitive strains specific for SCF core components (Skp1, Cullin (Cdc53), E2 enzyme (Cdc34)) and the F-box protein Cdc4.
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2011-06-30 | E-GEOD-22271 | biostudies-arrayexpress
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