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TranscriptomicsCooperative Signaling Through the STAT3 and NF-kB Pathways in Subtypes of DLBCL
The activated B cell-like (ABC) subgroup of diffuse large B cell lymphoma (DLBCL) is characterized by constitutive activation of the NF-êB pathway. Here we show that the NF- êB pathway induces the expression of the cytokines IL-6 and IL-10 in ABC DLBCL cell lines, which also have high levels of to...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-10009 | biostudies-arrayexpress
UnknownRifampicin resistant <i>Mycobacterium tuberculosis</i> in Vietnam, 2020-2022.
Not available
S-EPMC10958107 | biostudies-literature
TranscriptomicsCompensatory IKKa activation of classical NF-kB signaling during IKKb inhibition
A subtype of diffuse large B-cell lymphoma (DLBCL), termed activated B-cell-like (ABC) DLBCL, depends on constitutive NF-kB pathway signaling for survival. Small molecule inhibitors of IkB kinase b (IKKb), a key regulator of the NF-kB pathway, kill ABC DLBCL cells and hold promise for the treatment ...
ORGANISM(S): Homo sapiens 
2009-06-01 | E-GEOD-11902 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiling of the Striatum in Shank3 Knockout ASD Rats: Effects of Early Swimming Regulation

OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
UnknownThe socioeconomic burden of chronic lung disease in low-resource settings across the globe - an observational FRESH AIR study.
Not available
S-EPMC6925865 | biostudies-literature
UnknownImplementing a context-driven awareness programme addressing household air pollution and tobacco: a FRESH AIR study.
Not available
S-EPMC7538921 | biostudies-literature
UnknownEffects and acceptability of implementing improved cookstoves and heaters to reduce household air pollution: a FRESH AIR study.
Not available
S-EPMC6695425 | biostudies-literature
UnknownNo time for change? Impact of contextual factors on the effect of training primary care healthcare workers in Kyrgyzstan and Vietnam on how to manage asthma in children - A FRESH AIR implementation study.
Not available
S-EPMC7730734 | biostudies-literature
UnknownMeasuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.
Not available
S-EPMC6227911 | biostudies-literature
UnknownGlobal, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.
Not available
S-EPMC6227504 | biostudies-literature
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