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MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
UnknownDose-adjusted EPOCH-rituximab combined with fludarabine provides an effective bridge to reduced-intensity allogeneic hematopoietic stem-cell transplantation in patients with lymphoid malignancies.
Not available
S-EPMC3295571 | biostudies-literature
UnknownImpact of Prognostic Discussions on the Patient-Physician Relationship: Prospective Cohort Study.
Not available
S-EPMC5773842 | biostudies-literature
ProteomicsTranscriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis
Activated cardiac fibroblasts (CF) play a central role in cardiac fibrosis, a condition associated with most cardiovascular diseases. Conversion of quiescent into activated CF sustains heart integrity upon injury. However, permanence of CF in active state inflicts deleterious heart function effects....
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD034244 | Pride
Cardiac fibroblasts  cardiac fibrosis  myofibroblasts  transcriptomics  quantitative proteomics 
MetabolomicsOrnithine Decarboxylase in Gastric Epithelial Cells Promotes the Immunopathogenesis of Helicobacter pylori Infection

Colonization by H. pylori is associated with a wide range of gastric diseases, ranging from superficial gastritis to more severe pathologies, including intestinal metaplasia and adenocarcinoma. The interplay of the host response and the pathogen affect the outcome of disease. One major component ...

2022-06-15 | MTBLS3235 | MetaboLights
UnknownTreatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841.
Not available
S-EPMC3269953 | biostudies-literature
UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
TranscriptomicsGene expression data from C.elegans
Numerous studies have shown that resistance to oxidative stress is crucial to stay healthy and to reduce the adverse effects of aging. Accordingly, nutritional interventions using antioxidant food-grade compounds or food products are currently an interesting option to help improve health and quality...
ORGANISM(S): Caenorhabditis elegans 
2012-12-31 | E-GEOD-42192 | biostudies-arrayexpress
MetabolomicsX chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

Statin drugs lower blood cholesterol levels for cardiovascular disease prevention. Women are more likely than men to experience adverse statin effects, particularly new-onset diabetes (NOD) and muscle weakness. Here we find that impaired glucose homeostasis and muscle weakness in statin-treated f...

2024-05-23 | MTBLS9677 | MetaboLights
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-12:36:36:554-60 - samples
The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.
EGAD00001003827 | EGA
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