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We selected and characterized doxorubicin/5FU resistant HCT-8/R clones from sensitive parental cells, analyzing several parameters: cell cycle phase distribution, apoptotic activity, expression, distribution and functionality of the P-gp efflux pump, ultrastructural features, invasiveness and transc...
ORGANISM(S): Homo sapiens 
Transcriptome profiling of Acute Myeloid Leukemia samples. This dataset includes patients with diagnosis of de novo or secondary AML who experienced non-HLA loss disease relapse after allo-HCT, and for whom paired pre- and post-transplant viable leukemic samples were available.
ORGANISM(S): Homo sapiens 
Transcriptome profiling of Acute Myeloid Leukemia samples. This dataset includes patients with diagnosis of de novo or secondary AML who experienced non-HLA loss disease relapse after allo-HCT, and for whom paired pre- and post-transplant viable leukemic samples were available.
ORGANISM(S): Homo sapiens 
In this study, we analyzed a total of 12 patients affected by pancreatic tumour split into two different groups based on their outcomes (6 good vs 6 worse prognoses). After the IHC of different populations within cancer, we randomly selected 3 patients for each group and performed a gene expression ...
ORGANISM(S): Homo sapiens 
Genotype profiling of Acute Myeloid Leukemia samples. This dataset includes patients with diagnosis of de novo or secondary AML who experienced non-HLA loss disease relapse after allo-HCT, and for whom paired pre- and post-transplant viable leukemic samples were available.
ORGANISM(S): Homo sapiens 
Dendritic cells (DCs) are professional antigen-presenting cells whose activity is intrinsically linked to the microenvironment. Hypoxia is a condition of low oxygen tension occurring in inflammatory tissues that creates a special microenvironment conditioning cell physiology. We studied the effects ...
ORGANISM(S): Homo sapiens 

We report a study of large rare, copy number variants (CNVs) in 192 patients with renal hypodysplasia (RHD). Congenital malformations of the kidney and urinary tract are present in 3 to 7 per 1,000 births, accounting for 16% of birth defects. These malformations account for 40-50% of pediatric an...

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