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TranscriptomicsAnalysis of Gene Expression in PTHrP-/- Mammary Buds
Analysis of Gene Expression in PTHrP-/- Mammary Buds Supports a Role for BMP Signaling and MMP2 in the Initiation of Ductal Morphogenesis. Parathyroid hormone-related protein (PTHrP) acts on the mammary mesenchyme and is required for proper embryonic mammary development. In order to understand PTHrP...
ORGANISM(S): Mus musculus 
2009-08-15 | E-GEOD-17654 | biostudies-arrayexpress
TranscriptomicsPMCA2 Regulates HER2 Expression, Cell-Surface Localization and Signaling, and Promotes HER2- Mediated Breast Cancer
In the normal breast, PMCA2 transports calcium into milk. It is also upregulated in breast cancer cells and high tumor levels predict increased mortality in patients. In this study, we examined interactions between PMCA2 and HER2. We find that PMCA2 and a scaffolding protein, NHERF1, interact to...
ORGANISM(S): Homo sapiens 
2014-10-22 | E-GEOD-62555 | biostudies-arrayexpress
UnknownTargeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Not available
S-EPMC6565370 | biostudies-literature
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