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TranscriptomicsPromoter Capture Hi-C of mouse ESC and TSC
Chromatin organisation of trophoblast stem cells (TSC) were compared with that of embryonic stem cells (ESC). The method enriches Hi-C libraries, to detect promoter interactions at restriction fragment level. We prepared Hi-C libraries from TSC and ESC (serum grown) samples and enriched them with a ...
ORGANISM(S): Mus musculus 
2018-09-05 | E-MTAB-6585 | biostudies-arrayexpress
TranscriptomicsMNase-Seq of isolated mono-nucleosomes from strains W303 (wild-type) and htz1∆.
Chromatin transactions are typically studied in vivo, or in vitro using artificial chromatin lacking the epigenetic complexity of the natural material. Attempting to bridge the gap between these approaches, we established a system for isolating the yeast genome as a library of mono-nucleosomes harbo...
ORGANISM(S): Saccharomyces cerevisiae S288c 
2019-05-08 | E-MTAB-7926 | biostudies-arrayexpress
GenomicsPromoter capture mESC and fetal liver
Genome organization influences transcriptional regulation by facilitating interactions between gene promoters and distal regulatory elements. To analyse distal promoter contacts we used Capture Hi-C (CHi-C) to enrich for promoter-interactions in HiC libraries from mouse ESC and E14.5 fetal liver. Pl...
ORGANISM(S): Mus musculus 
2015-02-01 | E-MTAB-2414 | biostudies-arrayexpress
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