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Biological Relevance and Intent of the Experiment Statin-associated muscle symptoms (SAMS) are among the most common adverse effects limiting the use of statin therapy, yet their underlying biological mechanisms remain poorly defined. While metabolic and structural causes have been proposed, increas...
ORGANISM(S): Homo sapiens 
Uterine stretch is thought to induce preterm labor in women with twin and higher order pregnancies, but the pathophysiology remains unclear. We investigated the pathogenesis of stretch-induced preterm birth for the first time in a pregnant nonhuman primate model. Eleven chronically catheterized preg...
ORGANISM(S): Macaca nemestrina 
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