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MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
MetabolomicsBiochemical changes in Robinia pseudoacacia leaflets in dependence of leaf mining, plant age and location

Plant responses to leaf-mining insects are still poorly studied, especially in woody species. Robinia pseudoacacia is widely cultivated in Ukraine, where it is not native. There, the trees are facing increasing damage from the likewise introduced leaf miner species Parectopa robiniel...

2026-03-20 | MTBLS14099 | MetaboLights
MetabolomicsMining for natural product antileishmanials in a fungal extract library
Leishmaniasis is a Neglected Tropical Disease caused by the insect-vector borne protozoan parasite, Leishmania species. Infection affects millions of the World’s poorest, however vaccines are absent and drug therapy limited. Recently, public-private partnerships have developed to identify new modes ...
2021-02-12 | MTBLS868 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (A)
Translational genomics, the use of model species to generate knowledge about biological processes and the functions of genes, offers great promise to biotechnologists. Few studies have sought robust responses of model plants to environmental stresses, such as salinity, by altering the stress dosage ...
2015-09-14 | MTBLS43 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (C)
Translational genomics, the use of model species to generate knowledge about biological processes and the functions of genes, offers great promise to biotechnologists. Few studies have sought robust responses of model plants to environmental stresses, such as salinity, by altering the stress dosage ...
2015-09-14 | MTBLS54 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (B)
Translational genomics, the use of model species to generate knowledge about biological processes and the functions of genes, offers great promise to biotechnologists. Few studies have sought robust responses of model plants to environmental stresses, such as salinity, by altering the stress dosage ...
2015-09-14 | MTBLS44 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (B)
New metabolic profiling technologies provide data on a wider range of metabolites than traditional targeted approaches. Metabolomic technologies currently facilitate acquisition of multivariate metabolic data using diverse, mostly hyphenated, chromatographic detection systems, such as GC-MS or liqui...
2015-09-14 | MTBLS41 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (C)
New metabolic profiling technologies provide data on a wider range of metabolites than traditional targeted approaches. Metabolomic technologies currently facilitate acquisition of multivariate metabolic data using diverse, mostly hyphenated, chromatographic detection systems, such as GC-MS or liqui...
2015-09-14 | MTBLS42 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (A)
New metabolic profiling technologies provide data on a wider range of metabolites than traditional targeted approaches. Metabolomic technologies currently facilitate acquisition of multivariate metabolic data using diverse, mostly hyphenated, chromatographic detection systems, such as GC-MS or liqui...
2015-09-14 | MTBLS22 | MetaboLights
MetabolomicshRUV: Hierarchical approach to removal of unwanted variation for large-scale metabolomics data
Liquid chromatography-mass spectrometry-based metabolomics studies are increasingly applied to large population cohorts, which run for several weeks or even years in data acquisition. This inevitably introduces unwanted intra- and inter-batch variations over time that can overshadow true biological ...
2021-07-05 | MTBLS2483 | MetaboLights
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