Sort   by:  
 Page size 
UnknownSystematic identification of recognition motifs for the hub protein LC8.
Not available
S-EPMC6607443 | biostudies-literature
ProteomicsLarge scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 disease specific mechanisms and vulnerabilities.
Coronaviruses constitute a constant threat as documented by the recent emergence of SARS-CoV-2 that has caused more than 2,5 million deaths worldwide. Despite this our understanding of coronaviruses and how they interact with their host is very limited. Here we describe a novel phage display library...
ORGANISM(S): Homo sapiens (Human) 
2021-10-29 | PXD025410 | Pride
Sars-cov2 Protein interaction Proteomics 
ProteomicsSIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1 

Objective: Brown adipose tissue (BAT) is important for thermoregulation in many mammals. Uncoupling protein 1 (UCP1) is the critical regulator of thermogenesis in BAT. Here we aimed to investigate the deacetylation control of BAT and to investigate a possible functional connection between UCP1 and s...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-18 | PXD013056 | Pride
Brown adipose tissue  thermogenesis  thermoregulation  mitochondria  uncoupling protein 1  sirtuin 3  acetylation  oxidative phosphorylation  fatty acid oxidation  acylcarnitines 
 
UnknownSIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1.
Not available
S-EPMC6601363 | biostudies-literature
UnknownLarge scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Not available
S-EPMC8605023 | biostudies-literature
ProteomicsSystematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling
Short linear motifs (SLiMs) form dynamic protein-protein interactions essential for signaling; however, sequence degeneracy and low binding affinities make them difficult to identify. In this study, we employed multiple, unbiased systematic approaches for SLiM discovery to elucidate the regulatory n...
ORGANISM(S): Homo sapiens (Human) 
2020-12-02 | PXD017868 | Pride
Signaling Calcium Short linear motifs (slims) Nuclear pore complex (npc) Intrinsically disordered proteins (idps) Phosphatase 
UnknownPD-1 blockade attenuates surgery-mediated immunosuppression and boosts Th1 immunity perioperatively in oesophagogastric junctional adenocarcinoma.
Not available
S-EPMC10288841 | biostudies-literature
UnknownELM-the Eukaryotic Linear Motif resource-2024 update.
Not available
S-EPMC10767929 | biostudies-literature
UnknownFatal meningoencephalitis associated with Ebola virus persistence in two survivors of Ebola virus disease in the Democratic Republic of the Congo: a case report study.
Not available
S-EPMC11464592 | biostudies-literature
UnknownStructural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium.
Not available
S-EPMC9734039 | biostudies-literature
Sort   by:  
 Page size