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MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
TranscriptomicsColony stimulating factor (CSF1) treatment of kidneys that have undergone ischemia reperfusion injury
Mice were subjected to renal artery clamps to induce ischemia/reperfusion injury to the kidney. 3 days post surgery mice were injected with CSF1 or PBS daily for a further 3 days. Mice were sacrificed 5 and 7 days post surgey and the kidney was removed and homogenised into single cell suspensions. C...
ORGANISM(S): Mus Musculus 
2011-06-20 | E-MTAB-557 | biostudies-arrayexpress
TranscriptomicsSRS endotype assignment of septic shock patients from the VANISH randomised trial
The aim of the experiment was to assign patients enrolled in the VANISH randomised trial to sepsis response signature (SRS) endotypes based on a previously published gene expression signature, in order to test for differential responses to treatment. VANISH was a double-blind randomised clinical tri...
ORGANISM(S): Homo sapiens 
2022-07-12 | E-MTAB-7581 | biostudies-arrayexpress
UnknownPerinatal nicotine exposure suppresses PPARγ epigenetically in lung alveolar interstitial fibroblasts.
Not available
S-EPMC4390504 | biostudies-literature
TranscriptomicsTime-course experiment
Buffy coat blood samples from 4 healthy donors were obtained from the Australian Red Cross Blood Service. The peripheral blood mononuclear cells were then extracted using a Ficoll Paque gradient. CD14 positive monocytes were then extracted using MACS (Miltenyi Biotec) magnetically labeled anti-CD14 ...
ORGANISM(S): Homo sapiens 
2011-02-02 | E-MEXP-2577 | biostudies-arrayexpress
UnknownEmpowering dog owners and One Health teams to eliminate rabies: A community-Led approach from Techiman metropolitan, Ghana.
Not available
S-EPMC12533445 | biostudies-literature
ProteomicsIn vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity
The Protein synthesis Using Recombinant Elements (PURE) system enables transcription and translation of a DNA template from purified components. Therefore, the PURE system-catalyzed generation of RNAs and proteins constituting the PURE system itself represents a major challenge toward a self-replica...
ORGANISM(S): Escherichia Coli 
2021-09-06 | PXD020877 | panorama
MetabolomicsEmerald ash borer (Agrilus planipennis) infestation bioassays and metabolic profiles of green ash (Fraxinus pennsylvanica) provide evidence for an induced host defensive response to larval infestation

INTRODUCTION: Larvae of the invasive emerald ash borer [EAB, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae)], kill over 99% of green ash (Fraxinus pennsylvanica Marshall) trees they infest, yet a small percentage of green ash (“linge...

2024-02-08 | MTBLS7999 | MetaboLights
ProteomicsArginine methylation during transcriptional arrest
The covalent attachment of methyl groups to the side-chain of arginine residues is known to play essential roles in regulation of transcription, protein function and RNA metabolism. The specific N-methylation of arginine residues is catalyzed by a small family of gene products known as protein argin...
ORGANISM(S): Homo sapiens (Human) 
2019-11-25 | PXD000559 | Pride
Human cell culture 
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