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UnknownPTEN is destabilized by phosphorylation on Thr366.
Not available
S-EPMC2267318 | biostudies-literature
UnknownDisruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.
Not available
S-EPMC3648380 | biostudies-literature
TranscriptomicsRole of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonel...
ORGANISM(S): Bos taurus 
2012-01-10 | E-GEOD-13847 | biostudies-arrayexpress
TranscriptomicsFunctional properties of PTEN and PTEN mutants in U87MG glioblastoma cells
To investigate the effects of PTEN activity on gene expression in 3D cultured glioblastoma cells and the contributions of PTEN's lipid and protein phosphatase activities to these effects. We expressed wild type PTEN, a catalytically dead mutant (C124S) or mutants selectively lacking protein or lipid...
ORGANISM(S): Homo sapiens 
2012-02-28 | E-MTAB-989 | biostudies-arrayexpress
UnknownSuppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.
Not available
S-EPMC2816976 | biostudies-literature
UnknownTemsirolimus with or without megestrol acetate and tamoxifen for endometrial cancer: a gynecologic oncology group study.
Not available
S-EPMC4063288 | biostudies-literature
UnknownIntensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.
Not available
S-EPMC6652154 | biostudies-literature
UnknownChildhood, adolescent, and young adulthood cancer risk in BRCA1 or BRCA2 pathogenic variant carriers.
Not available
S-EPMC11972678 | biostudies-literature
UnknownNeurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial.
Not available
S-EPMC5023520 | biostudies-literature
UnknownTocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8084355 | biostudies-literature
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