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TranscriptomicsTranscriptomic profiling of human neuromesodermal-like cells and spinal cord progenitors derived in vitro from H9 ES cell line
Human ES (H9) cells were directed towards a neuromesodermal progenitor-like cell state and these cells were then subsequently differentiated towards a neural cell fate. Human ES cells (H9) were differentiated into neuromesodermal progenitor-like cells by culturing in Neurobasal/1x N2/1x B27 medium (...
ORGANISM(S): Homo sapiens 
2018-07-04 | E-MTAB-6680 | biostudies-arrayexpress
TranscriptomicsInfluence of SUMOylation on transcriptional signature of hIPSCs (ChiPS4) assessed by time-resolved RNA-seq in response to ML792 treatment
SUMOylation is thought to regulate chromatin structure and accessibility thus affecting gene expression. In order to assess these potential roles of SUMOylation in human pluripotent stem cells, ChiPS4 cells were treated with ML792 (selective SUMO E1 inhibitor) or DMSO (vehicle control) for the follo...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-9962 | biostudies-arrayexpress
GenomicsLandscape of protein SUMOylation on chromatin in hIPSCs (ChiPS4) by SUMO1 CHIP-seq
SUMO1 CHIP-seq experiment was performed in untreated hiPSC line - ChiPS4, to determine the exact locations of chromatin bound SUMO1 in these cells, thus providing information about the landscape of SUMOylation of protein targets on chromatin in human pluripotent cells and as such allowing for invest...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-9960 | biostudies-arrayexpress
TranscriptomicsInfluence of SUMOylation on chromatin structure in hIPSCs (ChiPS4) assessed by time-resolved ATAC-seq in response to ML792 treatment
SUMOylation is thought to regulate chromatin structure and accessibility thus affecting gene expression. In order to assess these potential roles of SUMOylation in human pluripotent stem cells, ChiPS4 cells were treated with ML792 (selective SUMO E1 inhibitor) or DMSO (vehicle control) for the follo...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-9961 | biostudies-arrayexpress
Unknown3 dimensional modelling of early human brain development using optical projection tomography.
Not available
S-EPMC514604 | biostudies-literature
UnknownQuality standards for the management of alcohol-related liver disease: consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology ARLD special interest group.
Not available
S-EPMC10551993 | biostudies-literature
UnknownIntensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.
Not available
S-EPMC6652154 | biostudies-literature
UnknownTocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8084355 | biostudies-literature
UnknownAACR Project GENIE: Powering Precision Medicine through an International Consortium.
Not available
S-EPMC5611790 | biostudies-literature
UnknownQuantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants.
Not available
S-EPMC8896276 | biostudies-literature
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