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UnknownTiming and causes of mid-Holocene mammoth extinction on St. Paul Island, Alaska.
Not available
S-EPMC4995940 | biostudies-literature
UnknownPhysical activity and sedentary behaviour and their associations with clinical measures in axial spondyloarthritis.
Not available
S-EPMC7002460 | biostudies-literature
TranscriptomicsAT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity
Purpose: Deregulated phosphatidylinositol 3-kinase pathway signaling through AGC kinases including AKT, p70S6 kinase, PKA, SGK and Rho kinase, is a key driver of multiple cancers. The simultaneous inhibition of multiple AGC kinases may increase antitumor activity and minimize clinical resistance com...
ORGANISM(S): Homo sapiens 
2012-07-19 | E-GEOD-38008 | biostudies-arrayexpress
TranscriptomicsCitrullination of Histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma
Multiple myeloma (MM), an incurable plasma cell malignancy, requires localisation within the bone marrow in order to survive and proliferate. Interactions between the malignant plasma cell and bone marrow mesenchymal stem cell (BMMSC) are thought to be a critical determinant of this requirement, and...
ORGANISM(S): Homo sapiens 
2016-08-03 | E-GEOD-80608 | biostudies-arrayexpress
UnknownAutomated In-Line Artificial Intelligence Measured Global Longitudinal Shortening and Mitral Annular Plane Systolic Excursion: Reproducibility and Prognostic Significance.
Not available
S-EPMC9245823 | biostudies-literature
UnknownThe benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.
Not available
S-EPMC3386495 | biostudies-literature
GenomicsActivation of the Integrated Stress Response by a Jumonji Histone Demethylase Inhibitor Induces Pro-Apoptotic Metabolic Reprogramming in Multiple Myeloma
Regulation of gene expression by chromatin modification through methylation of histone lysine residues is a dynamic, reversible process that when deregulated is associated with cancer development. In multiple myeloma, combined inhibition of the histone demethylases JARID1B, UTX and JmjD3 by the smal...
ORGANISM(S): Homo sapiens 
2015-08-21 | E-GEOD-60626 | biostudies-arrayexpress
UnknownGlutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?
Not available
S-EPMC6035773 | biostudies-literature
GenomicsBASIS_KOREAN_DATASET - samples
A comprehensive characterisation and analysis of human breast cancers through whole-genome sequencing.
EGAD00001001322 | EGA
UnknownClarifying the effect of biodiversity on productivity in natural ecosystems with longitudinal data and methods for causal inference.
Not available
S-EPMC10163230 | biostudies-literature
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