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UnknownATP-binding cassette transporter-2 (ABCA2) as a therapeutic target.
Not available
S-EPMC5899931 | biostudies-literature
TranscriptomicsAffect of antiviral ribavirin on YFV WT and vaccine strains.
Live-attenuated viral vaccines have been successfully used to combat infectious disease for decades but due to their empirical derivation, little is known about their mechanisms of attenuation. This lack of understanding makes the development of next generation live attenuated vaccines difficult. Th...
ORGANISM(S): Yellow fever virus 
2020-01-01 | E-MTAB-8504 | biostudies-arrayexpress
ProteomicsSingle-cell census of the colonic epithelium reveals goblet cell drivers of barrier breakdown in inflammatory bowel disease
Colonic epithelial cells facilitate host-microbe interactions to control mucosal immunity, and they also coordinate recycling and forming the mucus barrier. Epithelial barrier breakdown underpins inflammatory bowel disease (IBD). However, we do not know the specific contributions of each epithelial ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-16 | PXD011655 | Pride
Human Inflammatory bowel disease Lc-ms/ms 
UnknownThe ATP-Binding Cassette Transporter-2 (ABCA2) Overexpression Modulates Sphingosine Levels and Transcription of the Amyloid Precursor Protein (APP) Gene.
Not available
S-EPMC4630823 | biostudies-literature
Unknown"Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system.
Not available
S-EPMC1800669 | biostudies-literature
UnknownActin-dependent recruitment of AGO2 to the zonula adherens.
Not available
S-EPMC10848941 | biostudies-literature
TranscriptomicsCaloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo
Caloric restriction (CR) without malnutrition is one of the most consistent strategies for increasing mean and maximal lifespan and delaying the onset of age-associated diseases. Stress resistance is a common trait of many long-lived mutants and life-extending interventions, including CR. Indeed, be...
ORGANISM(S): Mus musculus 
2015-08-06 | E-GEOD-67430 | biostudies-arrayexpress
UnknownDisruption of protein quality control of the human ether-a-go-go related gene K+ channel results in profound long QT syndrome.
Not available
S-EPMC8810706 | biostudies-literature
UnknownMentoring Strategies and Outcomes of Two Federally Funded Cancer Research Training Programs for Underrepresented Students in the Biomedical Sciences.
Not available
S-EPMC9122347 | biostudies-literature
UnknownAssociation of Blood Pressure With Brain White Matter Microstructural Integrity Assessed With MRI Diffusion Tensor Imaging in Healthy Young Adults.
Not available
S-EPMC11023804 | biostudies-literature
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