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TranscriptomicsCaloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo
Caloric restriction (CR) without malnutrition is one of the most consistent strategies for increasing mean and maximal lifespan and delaying the onset of age-associated diseases. Stress resistance is a common trait of many long-lived mutants and life-extending interventions, including CR. Indeed, be...
ORGANISM(S): Mus musculus 
2015-08-06 | E-GEOD-67430 | biostudies-arrayexpress
ProteomicsSingle-cell census of the colonic epithelium reveals goblet cell drivers of barrier breakdown in inflammatory bowel disease
Colonic epithelial cells facilitate host-microbe interactions to control mucosal immunity, and they also coordinate recycling and forming the mucus barrier. Epithelial barrier breakdown underpins inflammatory bowel disease (IBD). However, we do not know the specific contributions of each epithelial ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-16 | PXD011655 | Pride
Human Inflammatory bowel disease Lc-ms/ms 
UnknownDisruption of protein quality control of the human ether-a-go-go related gene K+ channel results in profound long QT syndrome.
Not available
S-EPMC8810706 | biostudies-literature
UnknownGenome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.
Not available
S-EPMC5802459 | biostudies-literature
UnknownAn epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.
Not available
S-EPMC7071645 | biostudies-literature
UnknownTMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone.
Not available
S-EPMC4395494 | biostudies-literature
UnknownA novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder.
Not available
S-EPMC9426662 | biostudies-literature
UnknownData envelopment analysis to evaluate the efficiency of tobacco treatment programs in the NCI Moonshot Cancer Center Cessation Initiative.
Not available
S-EPMC10173908 | biostudies-literature
GenomicsGenetic and Functional Drivers of Diffuse Large B Cell Lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common hematologic malignancy and is characterized by a striking degree of heterogeneity. We enrolled a total of 1001 DLBCL patients and comprehensively defined the landscape of genetic mutations, copy number alterations and expression through whole-...
EGAS00001002606 | EGA
UnknownDominant-negative variant in SLC1A4 causes an autosomal dominant epilepsy syndrome.
Not available
S-EPMC10270265 | biostudies-literature
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