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MetabolomicsIdentification of pre-diagnostic lipid sets associated with liver cancer risk using untargeted lipidomics and chemical set analysis – a nested case-control study within the ATBC cohort

In pre-disposed individuals, a reprogramming of the hepatic lipid metabolism may support liver cancer initiation. We conducted a high-resolution mass spectrometry based untargeted lipidomics analysis of pre-diagnostic serum samples from a nested case-control study (219 liver cancer cases and 219 ...

2023-09-18 | MTBLS7776 | MetaboLights
TranscriptomicsJnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
Hepatic fibrosis is a wound-healing response to chronic liver injury, which may result in cirrhosis and liver failure. The c-Jun N-terminal kinase-1 (JNK1) gene has been shown to be involved in liver fibrosis. Here, we aimed to investigate the molecular mechanism and identify the cell-type involved ...
ORGANISM(S): Mus musculus 
2013-11-27 | E-GEOD-40041 | biostudies-arrayexpress
UnknownGenomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer.
Not available
S-EPMC10181943 | biostudies-literature
UnknownCharacterization of Pulmonary Metastases in Children With Hepatoblastoma Treated on Children's Oncology Group Protocol AHEP0731 (The Treatment of Children With All Stages of Hepatoblastoma): A Report From the Children's Oncology Group.
Not available
S-EPMC5648177 | biostudies-literature
UnknownA Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170).
Not available
S-EPMC11264598 | biostudies-literature
TranscriptomicsTranscription profiling of lesional and non-lesional skin from actopic dermititis patients and normal skin
Atopic dermatitis (AD) is a common pruritic dermatitis with macroscopically nonlesional skin that is often abnormal. Therefore, we used high-density oligonucleotide arrays to identify cutaneous gene transcription changes associated with early AD inflammation as potential disease control targets. S...
ORGANISM(S): Homo sapiens 
2006-10-01 | E-GEOD-5667 | biostudies-arrayexpress
UnknownAntitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).
Not available
S-EPMC5941615 | biostudies-literature
UnknownDisappearance of the last tropical glaciers in the Western Pacific Warm Pool (Papua, Indonesia) appears imminent.
Not available
S-EPMC6936586 | biostudies-literature
UnknownA genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
Not available
S-EPMC6677735 | biostudies-literature
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
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