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MetabolomicsPhysiological and Molecular Dissection of Daily Variance in Exercise Capacity
Physical performance relies on the concerted action of myriad responses, many of which are under circadian clock control. Little is known, however, regarding the time-dependent effect on exercise performance at the molecular level. We found that both mice and humans exhibit daytime variance in exerc...
2019-04-07 | MTBLS145 | MetaboLights
TranscriptomicsTranscription profiling of mouse pancreatic islets on day 14.5 of pregnancy
The inability of the beta-cell to meet the demand for insulin brought about by insulin resistance leads to type 2 diabetes. In adults, beta-cell replication is one of the mechanisms thought to cause the expansion of beta-cell mass. Efforts to treat diabetes require knowledge of the pathways that dri...
ORGANISM(S): Mus musculus 
2010-06-26 | E-MTAB-120 | biostudies-arrayexpress
TranscriptomicsComparison of Saffron and Photobiomodulation on the light damaged rat retina.
Aim: To identify the genes and non-coding RNAs (ncRNAs) involved in the neuroprotective actions of a dietary anti-oxidant (saffron) and of photobiomodulation. Methods: We used a previously published assay of photoreceptor damage, in which albino Sprague Dawley rats raised in dim cyclic illumination ...
ORGANISM(S): Rattus norvegicus 
2010-07-16 | E-GEOD-22818 | biostudies-arrayexpress
UnknownEvaluation of a survivorship needs assessment planning tool for head and neck cancer survivor-caregiver dyads.
Not available
S-EPMC6478174 | biostudies-literature
TranscriptomicsGene regulation in the hyperoxia mouse retina
PURPOSE: Hyperoxia is toxic to photoreceptors, and this toxicity may be important in the progress of retinal dystrophies. This microarray study examines gene expression induced in the C57BL/6J mouse retina by hyperoxia over the 14-day period during which photoreceptors first resist, then succumb to,...
ORGANISM(S): Mus musculus 
2010-08-05 | E-GEOD-23437 | biostudies-arrayexpress
MetabolomicsSeasonal and day/night variations of microbial metabolic functioning in simulated cloud water

Microorganisms maintain metabolic activity in clouds, with recognized impacts on chemical reactivity by contributing to the processing of small organic compounds, radicals and their precursors. However, the conditions in clouds can be highly contrasted (temperature, light, etc), and it remains un...

2026-02-12 | MTBLS12281 | MetaboLights
MetabolomicsComparison of lipidome profiles of Caenorhabditis elegans—results from an inter-laboratory ring trial

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. D...
2022-02-21 | MTBLS2016 | MetaboLights
UnknownRandomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522.
Not available
S-EPMC4162493 | biostudies-literature
UnknownPhase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer.
Not available
S-EPMC4881374 | biostudies-literature
TranscriptomicsTranscription profiling of C. elegans treated with UV-C radiation
We used gene expression profiling to address several specific questions that arose in a study of repair of ultraviolet C radiation in C elegans, as well as to generate hypotheses regarding the possible mechanism(s) of decreased DNA repair observed in old adults in that study. This analysis was perfo...
ORGANISM(S): Caenorhabditis elegans 
2008-06-13 | E-GEOD-4766 | biostudies-arrayexpress
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