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TranscriptomicsTranscription profiling of mouse FVB/N embryonic yolk sacs eythroid and epithelial samples from day E9.5
Primitive erythropoiesis in the mouse yolk sac is followed by definitive erythropoiesis resulting in adult erythrocytes. In comparison to definitive erythropoiesis little is known about the genes that control the embryonic erythroid program. The purpose of this study was to generate a profile of mou...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10002 | biostudies-arrayexpress
UnknownClearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia.
Not available
S-EPMC6008108 | biostudies-literature
TranscriptomicsKLF2-Regulated Gene Expression in Mouse Embryonic Yolk Sac Erythroid Cells
KLF2 is a Krüppel-like zinc-finger transcription factor required for blood vessel, lung, T-cell, and erythroid development. KLF2-/- mice die by embryonic day 14.5 (E14.5), due to hemorrhaging and heart failure. Embryonic -like globin gene expression is reduced in KLF2-/- embryos compared to wildtype...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-27602 | biostudies-arrayexpress
TranscriptomicsKLF1, KLF2 and c-myc control a regulatory network essential for embryonic erythropoiesis
The Krüppel-like factors, KLF1 and KLF2, positively regulate embryonic β-globin expression, and have additional overlapping roles in embryonic (primitive) erythropoiesis. KLF1-/-KLF2-/- double knockout mice are anemic at embryonic day 10.5 (E10.5) and die by E11.5, in contrast to single knockouts. T...
ORGANISM(S): Mus musculus 
2012-03-12 | E-GEOD-36427 | biostudies-arrayexpress
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