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TranscriptomicsGlobal gene expression in response to West Nile virus in mouse spleen and liver
Purpose of this experiment was to further understand how innate immune defenses impact host response and West Nile virus tissue tropism. This study examined host-transcriptional response to West Nile virus in permissive and nonpermissive tissues using wildtype mice and mice with genetically altered ...
ORGANISM(S): Mus musculus 
2012-12-19 | E-GEOD-39259 | biostudies-arrayexpress
UnknownThe Influence of Exercise on Cardiovascular Health in Sedentary Adults With Human Immunodeficiency Virus.
Not available
S-EPMC5893400 | biostudies-literature
MetabolomicsOPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response

Ferroptosis, an iron-dependent form of nonapoptotic cell death mediated by lipid peroxidation, has been implicated in the pathogenesis of multiple diseases. Subcellular organelles play pivotal roles in the regulation of ferroptosis, but the mechanisms underlying the contributions of the mitochond...

2025-07-14 | MTBLS10544 | MetaboLights
UnknownIndacaterol acetate/mometasone furoate provides sustained improvements in lung function compared with salmeterol xinafoate/fluticasone propionate in patients with moderate-to-very-severe COPD: results from a Phase II randomized, double-blind 12-week study.
Not available
S-EPMC6287650 | biostudies-literature
TranscriptomicsGenomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant–Mediated Nephrotoxicity
The use of calcineurin inhibitor (CI) immunosuppressants has significantly improved the early allograft survival rate in organ transplantation. However, CI therapy has been associated with chronic nephrotoxicity, which limits their long-term utility. In order to understand the mechanisms of the toxi...
ORGANISM(S): Rattus norvegicus 
2011-11-23 | E-GEOD-19366 | biostudies-arrayexpress
UnknownCognitive assessment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a cognitive substudy of the multi-site clinical assessment of ME/CFS (MCAM).
Not available
S-EPMC11565701 | biostudies-literature
TranscriptomicsTranscription profiling of human immature dendritic cells treated with Lipopolysaccharide (LPS) vs Taxol (paclitaxel)
Generation of monocyte-derived dendritic cells (DC). Immature DC were prepared from peripheral blood mononuclear cells (PBMCs) isolated from whole blood of healthy donors. A minimum of 3 individual donor blood was used for each experiment. PBMCs were incubated with anti-CD14 microbeads (Miltenyi Bio...
ORGANISM(S): Homo sapiens 
2009-11-27 | E-MEXP-2465 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomic analysis of acute host responses during 2009 pandemic H1N1 influenza infection in mouse, macaque, and swine (swine dataset)
Background: The 2009 pandemic H1N1 influenza virus emerged in swine and quickly became a major global health threat. In mouse, non-human primate, and swine infection models, the pH1N1 virus efficiently replicates in the lung and induces pro-inflammatory host responses; however, whether similar or di...
ORGANISM(S): Sus scrofa 
2012-09-12 | E-GEOD-40847 | biostudies-arrayexpress
UnknownNatural killer cytotoxicity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a multi-site clinical assessment of ME/CFS (MCAM) sub-study.
Not available
S-EPMC10069115 | biostudies-literature
TranscriptomicsLong-Term Programming of Antigen-Specific Immunity from Gene Expression Signatures in the PBMC of Rhesus Macaques Immunized with an SIV DNA Vaccine
The primary objective of this study was to evaluate response to a SIV DNA-based vaccine that was adminstered via vivo electroporation (EP) in rhesus macaques to further understand the molecular correlates of protection against SIV. In this study, rhesus macaques were immunized with a DNA vaccine inc...
ORGANISM(S): Macaca mulatta 
2012-02-15 | E-GEOD-35816 | biostudies-arrayexpress
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