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MetabolomicsGeneration of a chromosome-scale genome assembly of the insect-repellent terpenoid-producing Lamiaceae species, Callicarpa americana

BACKGROUND: Plants exhibit wide chemical diversity due to the production of specialized metabolites that function as pollinator attractants, defensive compounds, and signaling molecules. Lamiaceae (mints) are known for their chemodiversity and have been cultivated for use as culi...

2020-12-04 | MTBLS1983 | MetaboLights
TranscriptomicsDietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9243 | biostudies-arrayexpress
TranscriptomicsHistone H3.3 and its proteolytically processed form drive a cellular senescence program
In this study, we have uncovered novel proteolytic processing of the histone H3 tail in senescence models in primary fibroblasts and melanocytes. Cleavage of H3 tail occurs at two distinct residues and is mediated by Cathepsin L. We show that variant H3.3 is preferentially cleaved, and that cleaved ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-55949 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wildtype or Hyp (X-linked hypophosphatemic) mouse kidney after feeding control or low phosphate diet to study changes in gene expression in response to low-phosphate diet.
This is a study of the change in gene expression in mouse kidney after feeding control (1.0% P) or low phosphate diet (0.03% P) for 3 or 5 days to normal or Hyp (X-linked hypophosphatemic) mice at 5 weeks of age. The mice were C57BL/6J. Normal wild-type mice, hemizygous Hyp (Hyp/Y) male mice, or h...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-868 | biostudies-arrayexpress
UnknownA Qualitative Study of Ecological Momentary Assessment of Suicide Risk for Persons Living With HIV in Philadelphia, PA, USA: Feasibility, Acceptability, and Ethical Implications.
Not available
S-EPMC12771506 | biostudies-literature
TranscriptomicsIn vivo gene expression data from wild type and CTLA-4 KO 5C.C7 T cells
CTLA-4 is thought to inhibit effector T cells both intrinsically, by competing with CD28 for B7 ligands, and extrinsically, through the action of regulatory T cells. We studied in vivo responses of normal and CTLA-4-deficient antigen-specific murine effector CD4+ T cells. In order to do these studie...
ORGANISM(S): Mus musculus 
2012-09-05 | E-GEOD-37563 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of hPSC-derived human intestinal organoids with endogenous vascular endothelial cells
The development of human pluripotent stem cell (hPSC)- derived small intestinal organoids (HIOs) has led to an improved understanding of human intestinal development and physiology. HIOs generated using directed differentiation lack some cellular populations found in the native organ, including vasc...
ORGANISM(S): Homo sapiens 
2020-12-20 | E-MTAB-9228 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
UnknownExtended Postpartum Medicaid In Colorado Associated With Increased Treatment For Perinatal Mood And Anxiety Disorders.
Not available
S-EPMC12038864 | biostudies-literature
TranscriptomicsHigh resolution temporal profiling of gene expression during Arabidopsis leaf development (senescence process)
Leaf senescence is an essential developmental process that involves altered regulation of thousands of genes and changes in many metabolic and signaling pathways resulting in massive physiological and structural changes in the leaf. The regulation of senescence is complex and although several senesc...
ORGANISM(S): Arabidopsis thaliana 
2011-03-24 | E-GEOD-22982 | biostudies-arrayexpress
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