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TranscriptomicsAnalysis of P-body (Dcp1) and Stress Granule (Pbp1) RNA content
Non-membrane-bound compartments such as mRNA processing bodies (PBs) and stress granules (SGs) play important roles in the regulation of gene expression following environmental stresses. Here we perform RIP-seq to determine the RNA interactors of Dcp1 (PB marker) and Pbp1 (SG marker) before and afte...
ORGANISM(S): Saccharomyces cerevisiae 
2021-09-30 | E-MTAB-9096 | biostudies-arrayexpress
TranscriptomicsRNAi knock down of mRNA decapping co-activators in Drosophila S2 cells
We analyzed mRNA expression profiles in Drosophila melanogaster S2 cells that had been depleted of proteins known as mRNA decapping co-activators. mRNA decapping is catalyzed by DCP2, and DCP2 activity is stimulated by decapping co-activators. This group of proteins includes DCP1, Hedls (also known ...
ORGANISM(S): Drosophila melanogaster 
2007-09-03 | E-MEXP-1012 | biostudies-arrayexpress
TranscriptomicsUncovering human DCP1 is essential for mRNA decapping process and paralog-specific functions in gene regulation
The decapping complex is crucial in regulating gene expression by removing the mRNA cap structure. While DCP2 serves as the catalytic subunit in this complex, DCP1 is recognized as its major activator. In humans, there exist two distinct paralogs of DCP1, DCP1a and DCP1b, which each form separate de...
ORGANISM(S): Homo sapiens 
2024-10-26 | GSE230847 | GEO
GenomicsAnalysis of P-body (Dcp1) and Stress Granule (Pbp1) RNA content
Analysis of P-body (Dcp1) and Stress Granule (Pbp1) RNA content
PRJEB38404 | ENA
GenomicsUncovering human DCP1 is essential for mRNA decapping process and paralog-specific functions in gene regulation
Uncovering human DCP1 is essential for mRNA decapping process and paralog-specific functions in gene regulation
PRJNA962829 | ENA
UnknownThe activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1.
Not available
S-EPMC4005699 | biostudies-literature
UnknownStructural basis of dcp2 recognition and activation by dcp1.
Not available
S-EPMC2323275 | biostudies-literature
UnknownDehydration stress activates Arabidopsis MPK6 to signal DCP1 phosphorylation.
Not available
S-EPMC3343339 | biostudies-literature
UnknownDCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa.
Not available
S-EPMC2789166 | biostudies-literature
UnknownHuman DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions.
Not available
S-EPMC11530239 | biostudies-literature
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