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TranscriptomicsThe gain-of-function AKT1E17K allele is oncogenic in mouse mammary gland
The gain-of-function mutation in the pleckstrin homology domain of AKT1 (AKT1E17K) occurs in lung and breast cancer. By use of human cellular models and of a AKT1E17K transgenic Cre-inducible murine strain (R26-AKT1E17K mice) we have demonstrated that AKT1E17K is a bona-fide oncogene for lung epithe...
ORGANISM(S): Mus musculus 
2022-06-01 | E-MTAB-7388 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with transcriptional Profile alterations (Expression)
Primary plasma cell leukaemia (pPCL) is a rare, yet aggressive form of de novo plasma cell tumor, distinguished from secondary PCL (sPCL) which represents a leukemic transformation of pre-existing multiple myeloma (MM). Here, we performed a comprehensive molecular analysis of a prospective series of...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-39381 | biostudies-arrayexpress
TranscriptomicsTranscriptional characterization of a prospective series of primary plasma cell leukemia revealed genes associated with tumor progression and poorest outcome
Plasma cell leukemia (PCL) is a rare form of plasma cell dyscrasia that presents either as a progression of previously diagnosed multiple myeloma (MM), namely secondary PCL (sPCL), or as the initial manifestation of disease, namely primary PCL (pPCL). Although presenting signs and symptoms include t...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-39925 | biostudies-arrayexpress
UnknownThe impact of vaccination status on post-acute sequelae in hospitalized COVID-19 survivors using a multi-disciplinary approach: An observational single center study.
Not available
S-EPMC11617281 | biostudies-literature
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
Not available
S-EPMC12512976 | biostudies-literature
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