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ProteomicsTermination of STING responses is mediated via ESCRT-dependent degradation
The cGAS-STING pathway forms a major component of the innate immune system. cGAS-STING signalling is induced by detection of either foreign (i.e. pathogenic) or mislocalised host double stranded (ds)DNA present within the cytosol. STING acts as the major signalling hub, where it controls activation ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-05 | PXD037108 | Pride
Cgas-sting/escrt/innate immunity/lysosomal degradation/vesicular trafficking 
TranscriptomicsThe anti-inflammatory nature of HDL in macrophages is mediated by ATF3
Elevated plasma levels of High Density Lipoprotein (HDL) are associated with decreased risk of cardiovascular disease (CVD). The protective role of HDL in atherosclerosis has been attributed primarily to its ability to remove excess cholesterol from lipid-laden macrophages (foam cells) within the ar...
ORGANISM(S): Mus musculus 
2013-12-08 | E-GEOD-44034 | biostudies-arrayexpress
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