De novo sphingolipid synthesis

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Acute proteome responses to de novo sphingolipid synthesis inhibition suggest cancer combination therapies

Sphingolipids are essential structural and signaling lipids that support membrane integrity and govern cell fate decisions. Whereas the consequences of chronic sphingolipid inhibition have been extensively explored, the immediate cellular responses to reduced sphingolipid levels remain poorly define...

ORGANISM(S): Homo sapiens (Human)

2026-06-08 | PXD079016 | Pride