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TranscriptomicsBiomarker genes highlight intraspecific and interspecific variations in the responses of Pinus taeda L. and Pinus radiata D. Don to Sirex noctilio F. acid gland secretions
Sirex noctilio F., a Eurasian horntail woodwasp recently introduced into North America, oviposits in pines and other conifers and in the process spreads a phytopathogenic fungus that serves as a food source for its larvae. During oviposition the woodwasp also deposits a mucus produced in its acid (...
ORGANISM(S): Pinus taeda 
2012-08-09 | E-GEOD-40000 | biostudies-arrayexpress
TranscriptomicsExpression changes in MEL cells upon differentiation and Ldb1 knockdown
Carbonic anhydrase 1 (Car1), an early specific marker of the erythroid differentiation, has been used to distinguish fetal and adult erythroid cells since its production closely follows the γ- to β-globin transition, but the molecular mechanism underlying transcriptional regulation of Car1 is unclea...
ORGANISM(S): Mus musculus 
2012-12-11 | E-GEOD-42839 | biostudies-arrayexpress
TranscriptomicsCell type specificity of chromatin organization mediated by CTCF and cohesin
CTCF sites are abundant in the genomes of diverse species but their function is enigmatic. We used chromosome conformation capture to determine long-range interactions among CTCF/cohesin sites over 2 Mb on human chromosome 11 encompassing the β-globin locus and flanking olfactory receptor genes. Alt...
ORGANISM(S): Homo sapiens 
2011-01-13 | E-GEOD-26507 | biostudies-arrayexpress
UnknownProlactin signaling drives tumorigenesis in human high grade serous ovarian cancer cells and in a spontaneous fallopian tube derived model.
Not available
S-EPMC6691889 | biostudies-literature
ProteomicsA helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis to promote parasite chronicity
The molecular mechanisms by which worm parasites evade host immunity are incompletely understood. In a mouse model of chronic intestinal helminth infection, we identify helminthic glutamate dehydrogenase (heGDH) as an essential factor for parasite chronicity by using antibody mediated neutralization...
ORGANISM(S): Homo sapiens (Human) 
2025-08-12 | PXD044102 | Pride
A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis to promote parasite chronicity 
TranscriptomicsRole of LDB1 in the transition from chromatin looping to transcription activation
Many questions remain about how close association of genes and distant enhancers occurs and how this is linked to transcription activation. In erythroid cells, LDB1 is recruited to the β-globin locus via LMO2 and is required for looping of the β-globin locus control region (LCR) to the active β-glob...
ORGANISM(S): Mus musculus 
2014-07-02 | E-GEOD-54549 | biostudies-arrayexpress
TranscriptomicsDistinct Ldb1/NLI complexes orchestrate γ-globin repression and re-activation through ETO2 in human adult erythroid cells.
The Ldb1/GATA-1/TAL1/LMO2 complex mediates long range interaction between the β-globin locus control region (LCR) and gene in adult mouse erythroid cells but whether this complex mediates chromatin interactions at other developmental stages or in human cells is unknown. We investigated human NLI (Ld...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-30047 | biostudies-arrayexpress
UnknownCervical screening uptake: A cross-sectional study of self-reported screening attitudes, behaviours and barriers to participation among South Asian immigrant women living in Australia.
Not available
S-EPMC9087249 | biostudies-literature
UnknownArtificial neural network to predict post-operative hypocalcemia following total thyroidectomy.
Not available
S-EPMC11306864 | biostudies-literature
UnknownEvaluation of Residency Applicant Preferences for Continuing Virtual Interviews: A National Database Analysis.
Not available
S-EPMC11838067 | biostudies-literature
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