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Using ChIP-Seq analysis we define genes induced in macrophages through synergistic transcriptional activation by NFkB and the IFNb-activated transcription factor ISGF3.
ORGANISM(S): Mus musculus 
To define the group of genes which is synergistically induced by cooperative activity of the type I interferon - activated Jak/STAT pathway and other pathways, we treated bone marrow-derived macrophages (BMDM) with heat-killed Listeria (hkL; non-STAT pathways activated), type I interferon alone (onl...
ORGANISM(S): Mus musculus 
Using ChIP-Seq analysis we define genes induced in macrophages through transcriptional activation by STAT1 and search for the gain of function in mutant Stat1Y701F compared to the Stat1-/- mice.
ORGANISM(S): Mus musculus 
We infected the bone marrow-derived macrophages (BMDM) isolated from WT, Stat1Y701F or Stat1-/- mice were infected with Listeria monocytogenes for 6, 12 or 24h, or left untreated in order to find out how the transcriptome of these genotypes differs during infection.
ORGANISM(S): Mus musculus 
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