Developmental and epileptic encephalopathy (DEE) caused by rare mutations in 118 different genes leads to profound disability and seizures starting in infancy. To generate models of developmental and epileptic encephalopathy, we used CRISPR/Cas9 to knock down 2 causative genes, ap3b2 (DEE48) and eef...
ORGANISM(S): Xenopus laevis
