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TranscriptomicsDefective structural RNA processing in relapsing-remitting multiple sclerosis
It is fundamentally unknown how normal cellular processes or responses to extracellular stimuli may invoke polyadenylation and degradation of ncRNA substrates or if human disease processes exhibit defects in polyadenylation of ncRNA substrates as part of their pathogenesis. Our results demonstrate t...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-GEOD-66573 | biostudies-arrayexpress
Transcriptomicsapum23_col3
Gene expression analyses of three-week old soil grown wild-type (Col-3) and apum23-1 mutant. Expression profiling was conducted as an attempt to identify the genes differentially regulated in apum23-1 mutant This study was under taken to characterize a member of pumilio family, APUM23 in Arabidopsis...
ORGANISM(S): Arabidopsis thaliana 
2011-03-01 | E-GEOD-23940 | biostudies-arrayexpress
ProteomicsNuclear VCP-like 2 (NVL2)-associated complex
LC-MSMS analysis of NVL2-associated pre-60S complex. To obtain more insights into the molecular mechanism of this effects caused by the mutant NVL2 in pre-60S complexes,we searched for additional proteins that preferentially interact with the NVL2(E365Q/E682Q) in comparison with wild-type NVL2. Co-m...
ORGANISM(S): Homo Sapiens (human) 
2025-01-31 | PXD057741 | JPOST Repository
UnknownNuclear Argonaute Piwi Gene Mutation Affects rRNA by Inducing rRNA Fragment Accumulation, Antisense Expression, and Defective Processing in Drosophila Ovaries.
Not available
S-EPMC7037970 | biostudies-literature
UnknownTranscription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly.
Not available
S-EPMC1927085 | biostudies-literature
GenomicsDefective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1 [RNA-seq]
Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1 [RNA-seq]
PRJNA866490 | ENA
GenomicsDefective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1 [3'RNA-seq]
Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1 [3'RNA-seq]
PRJNA866522 | ENA
TranscriptomicsDefective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1 [RNA-seq]
Decapping 5'-3' exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in ...
ORGANISM(S): Arabidopsis thaliana 
2025-02-11 | GSE210614 | GEO
TranscriptomicsiCLIP Analysis of WT, phospho-defective, and phospho-mimicking mutants of mouse Nucleolin in iKras PDAC cells
This experiment aimed to identify Nucleolin (Ncl) binding sites on a transcriptome-wide scale, by performing iCLIP in mouse iKras PDAC cells (Ying et al., 2012) transiently transfected with a mammalian expression construct encoding a wild-type (WT) myc-Ncl, a phospho-defective mutant in which S28, S...
ORGANISM(S): Mus musculus 
2023-03-01 | E-MTAB-12481 | biostudies-arrayexpress
TranscriptomicsDefective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1 [3'RNA-seq]
Decapping 5'-3' exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in ...
ORGANISM(S): Arabidopsis thaliana 
2025-02-11 | GSE210631 | GEO
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