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TranscriptomicsTranscription profiling of human fibroblasts stimulated with PDGF-BB or b-FGF
We analyzed gene expression in human fibroblasts stimulated by platelet-derived growth factor-BB (PDGF-BB) or basic fibroblast growth factor (bFGF) for 1h and 24h. The results of two independent experiments were merged. SAM analysis identified 116 relevant probe sets. Hierarchical clustering of thes...
ORGANISM(S): Homo sapiens 
2009-03-20 | E-GEOD-14256 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of neuroendocrine primary tumors: effect of Octreotide treatment
Gene expression profiles of primary neuroendocrine tumors treated or not with 1µM Octreotide.We investigated 5 human neuroendocrine cell lines, CNDT2.5 and KRJ1, established from ileum NETs, QGP1 by a pancreatic NET, NCI H720 and NCI H727 from bronchopulmonary NETs. CNDT2.5 cell wereconstantly treat...
ORGANISM(S): Homo sapiens 
2013-01-08 | E-MTAB-388 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neural stem cells treated with FGF-2, PDGF-AA or in the absence of growth factor (differentiation)
We compared the gene expression profiles of neural stem cells treated with FGF-2, PDGF-AA or in the absence of growth factor (differentiation). Cells grown in the presence of FGF-2 were used as a reference.
ORGANISM(S): Rattus norvegicus 
2006-03-15 | E-TABM-39 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of small-intestine neuroendocrine tumors and human neuroendocrine tumor cell lines
Small intestinal neuroendocrine tumors (SI-NETs) arise from serotonin-producing enterochromaffin cells. SI-NETs are often well-differentiated tumors and most patients have regional or distant metastases at initial presentation. MicroRNAs (miRs) are post-transcriptional regulators which are important...
ORGANISM(S): Homo sapiens 
2012-11-08 | E-MTAB-862 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fibroblasts infected with adenoviruses encoding for STREBP1c
We compared the gene expression profiles of AG01518 human fibroblasts infected with adenoviruses encoding for SREBP1c. Cells infected with mock virus are used as a reference.
ORGANISM(S): Homo sapiens 
2007-04-26 | E-TABM-215 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human G01518 fibroblasts starved for 16 hours in the presence of 0.1% BSA, and then stimulated for 1, 4, 10 or 24 hours with PDGF-BB (10 ng/ml in starvation medium),
Subconfluent AG01518 fibroblasts were starved for 16 hours in the presence of 0.1% BSA, and then stimulated for 1, 4, 10 or 24 hours with PDGF-BB (10 ng/ml in starvation medium), or left untreated for the same periods of time. Total RNA was isolated using the RNeasy kit (Qiagen). The RNA quality was...
ORGANISM(S): Homo sapiens 
2004-06-30 | E-MEXP-126 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human classical midgut carcinoid primary tumors and liver metastasis
We identify genes presenting a specific expression profile in midgut carcinoid cells, primary carcinoids tumors and liver metastasis were gene profiled. Gene expression profiling of classical midgut carcinoid primary tumors and liver metastasis reveal potential novel therapeutic targets and molecula...
ORGANISM(S): Homo sapiens 
2008-11-13 | E-GEOD-9576 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of imatinib-treated and untreated human Hematopoetic progenitors expressing the ETV6-PDGFRB oncogene
In order to investigate the mechanism whereby TEL-PDGF-beta (ETV6-PDGFRB) interferes with human hematopoietic progenitors proliferation and differentiation, we analyzed the gene expression response downstream this oncogene. CD34+ cells infected with lentivirus coding for TEL-PDGFRb were cultured for...
ORGANISM(S): Homo sapiens 
2012-04-09 | E-GEOD-28698 | biostudies-arrayexpress
TranscriptomicsPDGF stimulation kinetics
Subconfluent AG01518 fibroblasts were starved for 16 hours in the presence of 0.1% BSA, and then stimulated for 1, 4, 10 or 24 hours with PDGF-BB (10 ng/ml in starvation medium), or left untreated for the same periods of time. Total RNA was isolated using the RNeasy kit (Qiagen). The RNA quality was...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1484 | biostudies-arrayexpress
Transcriptomicsthe influence of a modification of the gut microbiota composition on the hepatic steatosis induced by n-3 polyunsaturated fatty acid (PUFA) depletion
in the present study, we evaluated whether microbiota modulation is able to restore hepatic steatosis induced by n-3 PUFA depletion in mice. For this purpose, mice were fed during three months with a n-3 PUFA-depleted diet (presenting a high n-6/n-3 PUFA ratio), and then supplemented with fructoolig...
ORGANISM(S): Mus musculus 
2012-12-12 | E-GEOD-31727 | biostudies-arrayexpress
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