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UnknownTNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.
Not available
S-EPMC12521918 | biostudies-literature
TranscriptomicssiRNA knock down of RIP140 in the presence of retinoic acid vs controls to investigate the role of RIP140 in retinoid mediated signaling
Cell-and context-specific activities of nuclear receptors may in part be due to distinct coregulator complexes recruited to distinct subsets of target genes. RIP140 (also called NRIP1) is a ligand-dependent corepressor that is inducible with retinoic acid (RA). We have shown previously that silen...
ORGANISM(S): Homo sapiens 
2008-04-04 | E-GEOD-7500 | biostudies-arrayexpress
ProteomicsThe senescence-associated cell surfaceome reveals potential senotherapeutic targets in human and mouse cells
Excessive accumulation of senescent cells contributes to a wide range of physiological declines and age-related pathologies. Senotherapy targeting senescent cell surface molecules represents an attractive approach to eliminate senescent cells with high specificity and accessibility. However, the com...
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2025-01-26 | PXD048921 | JPOST Repository
TranscriptomicsGR and ER co-activation alters the expression of differentiation genes and associates with improved ER+ breast cancer outcome
Analysis of MCF-7 cells treated for 4h with Ethanol, Estradiol (E2), Dexamethasone (Dex), or Estradiol + Dexamethasone (E2 + Dex) In estrogen receptor (ER)-negative breast cancer (BC), high tumor glucocorticoid receptor (GR) expression has been associated with a relatively poor outcome. In contrast...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-79761 | biostudies-arrayexpress
UnknownLong-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial.
Not available
S-EPMC4858585 | biostudies-literature
UnknownViral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon.
Not available
S-EPMC6469509 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
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