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TranscriptomicsExpression data from a human MLL-AF6 positive AML cell line
The MLL gene on chromosome 11 fuses to the AF6 gene on chromosome 6 in a balanced chromosomal translocation that is characetristic of certain adult and pediatric human leukemias. We established a murine leukemia model of MLL-AF6 using the retroviral MLL-AF6 contruct in a bone marrow transplantation ...
ORGANISM(S): Homo sapiens 
2013-04-03 | E-GEOD-43068 | biostudies-arrayexpress
GenomicsGenome wide mapping of histone 3 lysine 79 dimethylation in MLL-AF6 murine leukemias
We report the genome wide distribution of H3K79 dimethylation in mouse MLL-AF6 positive leukemias to assess whether this epigenetic mark drives MLL-target gene expression. Examination of H3K79 dimethylation in bone marrow cells from sacrificed terminally ill MLL-AF6 positive leukemic mice. The retr...
ORGANISM(S): Mus musculus 
2013-04-03 | E-GEOD-43062 | biostudies-arrayexpress
TranscriptomicsExpression data from MLL-AF6 positive leukemia cells
The MLL gene on chromosome 11 fuses to the AF6 gene on chromosome 6 in a balanced chromosomal translocation that is characetristic of certain adult and pediatric human leukemias. We established a murine leukemia model of MLL-AF6 using the retroviral MLL-AF6 contruct in a bone marrow transplantation ...
ORGANISM(S): Mus musculus 
2013-04-03 | E-GEOD-43067 | biostudies-arrayexpress
GenomicsGenome wide mapping of histone 3 lysine 79 dimethylation in MLL rearranged and control human leukemia cell lines
We report the genome wide distribution of H3K79 dimethylation in the human MLL-AF6 rearranged cell line ML2 as well as the human MOLM13 and HL60 cell lines Examination of H3K79 dimethylation in the MLL-AF6 fusion positive human leukemia cell line ML2 and control cell lines MOLM-13 and HL60. The MLL...
ORGANISM(S): Homo sapiens 
2013-04-03 | E-GEOD-43063 | biostudies-arrayexpress
UnknownDecoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile.
Not available
S-EPMC10338468 | biostudies-literature
UnknownA systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing.
Not available
S-EPMC8586238 | biostudies-literature
UnknownAcute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1.
Not available
S-EPMC10586237 | biostudies-literature
ProteomicsRNF5 interactome
Cells expressing Flag-tagged RNF5 or empty vector were incubated with the proteasome inhibitor MG132 to block protein degradation. Cell lysates were then prepared and immunoprecipitationed with anti-Flag antibody were performed, and eluates were digested with trypsin and analyzed on a Q Exactive.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-11-25 | MSV000083160 | MassIVE
UnknownFitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.
Not available
S-EPMC2646274 | biostudies-literature
UnknownElasticity of the HIV-1 core facilitates nuclear entry and infection.
Not available
S-EPMC11419384 | biostudies-literature
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