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GenomicsDesmosome mutations impact the tumor microenvironment to promote melanoma proliferation [Spatial transcriptomics]
Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation [Spatial transcriptomics]
PRJNA1232113 | ENA
GenomicsDesmosome mutations impact the tumor microenvironment to promote melanoma proliferation [scRNA-seq]
Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation [scRNA-seq]
PRJNA1232122 | ENA
TranscriptomicsDesmosome mutations impact the tumor microenvironment to promote melanoma proliferation [scRNA-seq]
Desmosomes are transmembrane protein complexes that contribute to cell-cell adhesion in epithelia and other tissues. Here, we report the discovery of frequent genetic alterations in the desmosome in human cancers, with the strongest signal seen in cutaneous melanoma where desmosomes are mutated in >...
ORGANISM(S): Homo sapiens 
2025-03-08 | GSE291160 | GEO
OtherDesmosome mutations impact the tumor microenvironment to promote melanoma proliferation [Spatial transcriptomics]
Desmosomes are transmembrane protein complexes that contribute to cell-cell adhesion in epithelia and other tissues. Here, we report the discovery of frequent genetic alterations in the desmosome in human cancers, with the strongest signal seen in cutaneous melanoma where desmosomes are mutated in >...
ORGANISM(S): Homo sapiens 
2025-03-05 | GSE291159 | GEO
UnknownDesmosome assembly and disassembly are membrane raft-dependent.
Not available
S-EPMC3907498 | biostudies-literature
UnknownPalmitoylation of plakophilin is required for desmosome assembly.
Not available
S-EPMC4150063 | biostudies-literature
GenomicsDisruption of tuftelin 1, a desmosome associated protein,causesskin fragility, woolly hair and palmoplantar keratoderma
Disruption of tuftelin 1, a desmosome associated protein,causesskin fragility, woolly hair and palmoplantar keratoderma
PRJNA997343 | ENA
UnknownE-cadherin binds to desmoglein to facilitate desmosome assembly.
Not available
S-EPMC6066328 | biostudies-literature
UnknownDesmosome mutations impact the tumor microenvironment to promote melanoma proliferation.
Not available
S-EPMC10541613 | biostudies-literature
UnknownRoles for Ndel1 in keratin organization and desmosome function.
Not available
S-EPMC8684757 | biostudies-literature
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