Sort   by:  
 Page size 
ProteomicsActivity-based profiling of deubiquitylating enzymes
This set is a repackaging of PXD031848 (described in https://doi.org/10.3390/ijms23063263: "ABPP-HT*-Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods") to make each LC-MS/MS experiment individually downloadable and to include TIMSC...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-24 | MSV000095426 | MassIVE
ProteomicsABPP-HT* - Deep meets fast for activity-based profiling of deubiquitylating enzymes using advanced DIA mass spectrometry methodsABPP-HT* - Deep meets fast for activity-based profiling of deubiquitylating enzymes using advanced DIA mass spectrometry methods
Activity-based protein profiling (ABPP) uses a combination of activity-based chemical probes with mass spectrometry (MS) to selectively characterise a particular enzyme or enzyme class. ABPP has proven invaluable for profiling enzymatic inhibitors in drug discovery. When applied to cell extracts and...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD031848 | Pride
Data-independent acquisition mass spectrometry (dia) Drug discovery Proteomics Activitomics Mass spectrometry Chemical biology Deubiquitylating enzymes Ubiquitin Activity-based probes 
UnknownDeubiquitylating enzymes in neuronal health and disease.
Not available
S-EPMC7822931 | biostudies-literature
UnknownDeubiquitylating Enzymes in Cancer and Immunity.
Not available
S-EPMC10754134 | biostudies-literature
UnknownSelenocysteine as a Latent Bioorthogonal Electrophilic Probe for Deubiquitylating Enzymes.
Not available
S-EPMC5550359 | biostudies-literature
UnknownDeubiquitylating enzymes and drug discovery: emerging opportunities.
Not available
S-EPMC7097658 | biostudies-literature
UnknownDUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT Proteins.
Not available
S-EPMC5218808 | biostudies-literature
UnknownSystematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity.
Not available
S-EPMC4183562 | biostudies-literature
UnknownThe emerging role of deubiquitylating enzymes as therapeutic targets in cancer metabolism.
Not available
S-EPMC8935717 | biostudies-literature
ProteomicsABPP-HT - high-throughput activity-based profiling of deubiquitylating enzyme inhibitors in a cellular context
The potency and selectivity of a small molecule inhibitor are key parameters to assess during the early stages of drug discovery. In particular, it is very informative for characterizing compounds in a relevant cellular context in order to reveal potential off-target effects and drug efficacy. Activ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-02-24 | PXD023036 | Pride
Drug discovery Pharmacology Activitomics Deubiquitylating enzymes Ubiquitin Automation Activity-based probes 
Sort   by:  
 Page size