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UnknownPrehospital use of magnesium sulfate as neuroprotection in acute stroke.

Background

Magnesium sulfate is neuroprotective in preclinical models of stroke and has shown signals of potential efficacy with an acceptable safety profile when delivered early after stroke onset in humans. Delayed initiation of neuroprotective agents has hindered earlier phase 3 trials of...
S-EPMC4920545 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
White matter hyperintensities of presumed vascular origin (WMH) are associated with cognitive impairment and are a key imaging marker in evaluating brain health. However, WMH volume alone does not fully account for the extent of cognitive deficits and the mechanisms linking WMH to these deficits rem...
S-EPMC11629703 | biostudies-literature
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