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TranscriptomicsDNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
Elevated DNA methylation in the first intronic region of the BCL6 locus in B cell lymphomas enforces transcription of the BCL6 gene Promoter tiling arrays were used to investigate the distribution of DNA methylation near the promoter region of BCL6 locus Comparison of DNA methylation at promoter reg...
ORGANISM(S): Homo sapiens 
2010-08-20 | E-GEOD-22884 | biostudies-arrayexpress
GenomicsRNA Polymerase II Pausing Can Be Retained or Acquired During Activation of Genes Involved in the Epithelial to Mesenchymal Transition
Promoter-proximal RNA polymerase II (Pol II) pausing is implicated in the regulation of gene transcription. However, the mechanisms of pausing including its dynamics during transcriptional responses remain to be fully understood. We performed global analysis of short capped RNAs and Pol II Chromatin...
ORGANISM(S): Homo sapiens 
2015-03-27 | E-GEOD-67041 | biostudies-arrayexpress
UnknownRNA Polymerase II Pausing Can Be Retained or Acquired During Activation of Genes Involved in the Epithelial to Mesenchymal Transition
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-67041 | biostudies-other
TranscriptomicsThe transcription factors Snail and Slug activate the TGF-B signaling pathway in breast cancer
Gene expression profiling to determine transcriptome changes following Snail or Slug expression in MCF-7 breast cancer cells Samples were isolated in three biological replicates for microarray analysis. Four MCF-7 breast cancer cell subsets: MCF-7(untreated), MCF-7 (with Control adenovirus), MCF-7 ...
ORGANISM(S): Homo sapiens 
2011-10-20 | E-GEOD-29672 | biostudies-arrayexpress
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