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TranscriptomicsTranscription profiling of human dendritic cells to identify a combinatorial code by which DCs discriminate pathogens and provide (suggest) a rationale to design adjuvants for TH1 responses.
Toll like receptors (TLRs) sense microbial products and initiate adaptive immune responses by activating dendritic cells (DCs). Since pathogens may contain several agonists we asked whether different TLRs may synergize in DC activation. We report that in human and mouse DC TLR3 or TLR4 potently syne...
ORGANISM(S): Homo sapiens 
2007-09-14 | E-GEOD-2706 | biostudies-arrayexpress
UnknownEnhanced recovery after bariatric surgery: a comprehensive survey-based analysis of ERABS actual clinical implementation in Italian bariatric centers.
Not available
S-EPMC12540566 | biostudies-literature
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
UnknownGalectin-3: One Molecule for an Alphabet of Diseases, from A to Z.
Not available
S-EPMC5855601 | biostudies-literature
UnknownComplete Pseudo-Anodontia in an Adult Woman with Pseudo-Hypoparathyroidism Type 1a: A New Additional Nonclassical Feature?
Not available
S-EPMC9777483 | biostudies-literature
UnknownAnalysis of survival rate and persistence predictors of baricitinib in real-world data from a large cohort of rheumatoid arthritis patients.
Not available
S-EPMC10899020 | biostudies-literature
UnknownA novel approach for studying receptor-ligand interactions on living cells surface by using NUS/T1ρ-NMR methodologies combined with computational techniques: The RGDechi15D-αvβ5 integrin complex.
Not available
S-EPMC8207173 | biostudies-literature
TranscriptomicsTranscription profiling and genotyping of 26 human mantle cell lymphoma samples
Among B-cell lymphomas mantle cell lymphoma (MCL) has the worst prognosis. By using a combination of genomic and expression profiling (Affymetrix GeneChip Mapping 10k Xba131 and U133 set), we analysed 26 MCL samples to identify genes relevant to MCL pathogenesis and that could represent new therapeu...
ORGANISM(S): Homo sapiens 
2007-06-24 | E-GEOD-4176 | biostudies-arrayexpress
UnknownA multifunctional locus controls motor neuron differentiation through short and long non coding RNAs
Not available
S-SCDT-EMBOJ-2021-108918 | biostudies-other
TranscriptomicsIdentification of novel genes associated with human glioblastoma (GBM) tumor-initiating cells (TICs)
Most patients affected by Glioblastoma multiforme (GBM) experience a recurrence of the disease because of the spreading of tumor-initiating cells (TICs) beyond surgical boundary. Unveiling and targeting molecular mechanisms causing this process is a logic goal to impair GBM killing ability. In an or...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-16805 | biostudies-arrayexpress
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