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One of the most economically important grapevine diseases is Downy mildew (DM) caused by the oomycete Plasmopara viticola. A strategy to reduce the use of fungicides to compensate for the high susceptibility of V. vinifera is the selection of grapevine varieties showing pathogen-specif...
2021-07-07 | MTBLS2876 | MetaboLights
Transfection of human myoblasts was performed using Lipofectamine or electroporation. Skeletal muscle myoblasts isolated from a human male donor were transfected using the Lipofectamine™ 2000 Transfection Reagent (Invitrogen, 11668019). Twenty-four hours before transfections, cells were plated to a ...
ORGANISM(S): Homo sapiens 
C2C12 (ATCC, #CRL-1772), a myoblast cell line from the C3H mouse strain, was grown in DMEM (Dulbecco’s Modified Eagle’s Medium, Gibco), supplemented with 10% fetal bovine serum (FBS) (Euroclone, Pero, Italy) and 2 mM L-glutamine (Gibco), and maintained in culture at 37 °C with 5% CO₂, without reachi...
ORGANISM(S): Mus musculus 
All-trans retinoic (ATRA) is used in the treatment of acute promyelocytic leukemia a rare form of AML characterized by the presence of a specific translocation involving chrosomes 15;17 and causing the production of the PML-RARα fusion protein in 95% of the cases. ATRA differentiates the APL blasts...
ORGANISM(S): Homo sapiens 

Grapevine (Vitis spp.) is a crop of major economic importance in Europe. Rising temperatures and extreme weather events reduce yield and alter berry composition, affecting wine quality. Despite advances in vineyard management, mechanisms underlying grapevine thermotolerance remain poorly understo...

2026-06-26 | MTBLS13195 | MetaboLights
Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease characterized by chromosomal aberrations of prognostic significance. Recent studies showed that gain of chromosome 2p is a recurrent lesion in CLL. We investigated the 2p gain and its relationship with prognostic biomarkers in ...
ORGANISM(S): Homo sapiens 
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