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ProteomicsColumbamide
Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering New Natural Products from Cyanobacteria Karin Kleigrewe, Jehad Almaliti, Isaac Yuheng Tian, Robin B. Kinnel, Anton Korobeynikov, Emily A. Monroe, Brendan M. Duggan, Vincenzo Di Marzo, David ...
ORGANISM(S): Cyanobacteria (ncbitaxon:1117) 
2015-01-26 | MSV000079016 | MassIVE
MetabolomicsGNPS - Columbamide massive dataset
Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering New Natural Products from Cyanobacteria Karin Kleigrewe, Jehad Almaliti, Isaac Yuheng Tian, Robin B. Kinnel, Anton Korobeynikov, Emily A. Monroe, Brendan M. Duggan, Vincenzo Di Marzo, David ...
ORGANISM(S): Cyanobacteria (ncbitaxon:1117) 
2015-01-26 | MSV000079016 | GNPS
UnknownOrexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity.

Objective

Orexin-A (OX-A) is a neuropeptide produced selectively by neurons of the lateral hypothalamus. It exerts powerful control over brain function and physiology by regulating energy homeostasis and complex behaviors linked to arousal. Under conditions of chronic or acute brain leptin s...
S-EPMC10122056 | biostudies-literature
UnknownPositive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer's disease.
A regular sleep-wake cycle plays a positive function that preserves synaptic plasticity and brain activity from neuropathological injuries. The hypothalamic neuropeptide orexin-A (OX-A) is central in sleep-wake regulation and has been found to be over-expressed in the cerebrospinal fluid (CSF) of pa...
S-EPMC9710385 | biostudies-literature
ProteomicsPrioritisation, Identification, and Quantification of Emerging Contaminants in Recycled Textiles Using Non-Targeted and Suspect Screening Workflows by LC-ESI-HRMS
Recycled textile samples obtained in Sweden, 2021. Multi-residue extraction method used. Top-5 DDA + Inclusion List employed for MS2 acquisition. mzML files converted from raw data (ProteoWizard::msConvert).
ORGANISM(S): Na 
2024-06-29 | MSV000095185 | MassIVE
UnknownThe Autoinflammatory Diseases Alliance Registry of monogenic autoinflammatory diseases.

Objective

The present manuscript aims to describe an international, electronic-based, user-friendly and interoperable patient registry for monogenic autoinflammatory diseases (mAIDs), developed in the contest of the Autoinflammatory Diseases Alliance (AIDA) Network.

Methods

This is an...
S-EPMC9500177 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.

Background

Pulmonary complications are the most common cause of death after surgery. This study aimed to derive and externally validate a novel prognostic model that can be used before elective surgery to estimate the risk of postoperative pulmonary complications and to support resource allo...
S-EPMC12056793 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

Background

Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.

Methods

The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death ...
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing ele...
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at...
S-EPMC8652887 | biostudies-literature
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