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TranscriptomicsEnvironmental factors transmitted by aryl hydrocarbon receptor influence severity of psoriatic skin inflammation [Affymetrix]
Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanism is unknown. Here we show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. AhR-activati...
ORGANISM(S): Mus musculus 
2014-06-11 | E-GEOD-47607 | biostudies-arrayexpress
TranscriptomicsEnvironmental factors transmitted by aryl hydrocarbon receptor influence severity of psoriatic skin inflammation [RNA-Seq]
Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanism is unknown. Here we show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. AhR-activati...
ORGANISM(S): Homo sapiens 
2014-06-11 | E-GEOD-47944 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of lymphoblastic cells, fat and skin from twins
Gene expression was quantified in LCL, skin and fat derived from a subset of Twins UK (N=156 LCL, N=160 skin, N=166 fat) using Illuminas whole genome expression array (HumanHT-12 version 3). Cis eQTL analysis was performed in each tissue, following by multiple analyses assessing the tissue-specifici...
ORGANISM(S): Homo sapiens 
2011-02-03 | E-MTAB-522 | biostudies-arrayexpress
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