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TranscriptomicsGenomic aberrations in distant fields from oral potentially malignant lesions by high resolution DNA flow cytometry and array-CGH
The aim of the study was to address the concept of field cancerization in oral cancer. The presence of genomic aberrations, indicative of chromosomal instability (CIN), in oral distant fields (ODFs) of visually normal and non-dysplastic mucosa at the mirror image from concomitant oral potentially ma...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-28906 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type and Ctip2-/- (Bcl11b) mutant striatum at P0
Striatal medium spiny neurons (MSN) are critically involved in motor control, and their degeneration is a principal component of Huntington’s disease. We find that the transcription factor Ctip2 (also known as Bcl11b) is central to MSN differentiation and striatal development. Within the striatum,...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9330 | biostudies-arrayexpress
UnknownBehavior, body composition, and vascular phenotype of homocystinuric mice on methionine-restricted diet or enzyme replacement therapy.
Not available
S-EPMC6902697 | biostudies-literature
UnknownThe <i>ENTPD1</i> promoter polymorphism -860 A > G (rs3814159) is associated with increased gene transcription, protein expression, CD39/NTPDase1 enzymatic activity, and thromboembolism risk.
Not available
S-EPMC6137499 | biostudies-literature
UnknownCirculating myomiRNAs as biomarkers in patients with Cushing's syndrome.
Not available
S-EPMC10904409 | biostudies-literature
UnknownMedical Treatment of Cushing's Disease: An Overview of the Current and Recent Clinical Trials.
Not available
S-EPMC7753248 | biostudies-literature
TranscriptomicsEnvironmental factors transmitted by aryl hydrocarbon receptor influence severity of psoriatic skin inflammation [Affymetrix]
Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanism is unknown. Here we show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. AhR-activati...
ORGANISM(S): Mus musculus 
2014-06-11 | E-GEOD-47607 | biostudies-arrayexpress
UnknownComparative Analysis of Commercial and Home-Made Media on RSPO1/S6R Axis in Organoids with Different Wnt Backgrounds: A Methodological Guide for the Selection of Intestinal Patient-Derived Organoids Culture Media.
Not available
S-EPMC11546270 | biostudies-literature
TranscriptomicsBlood transcriptomics of drug-naive sporadic Parkinson'?s disease patients
Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder that is clinically defined in terms of motor symptoms. These are preceded by prodromal non-motor manifestations that prove the systemic nature of the disease. Identifying genes and pathways altered in living patients provid...
ORGANISM(S): Homo sapiens 
2015-10-29 | E-GEOD-72267 | biostudies-arrayexpress
UnknownNeutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury.
Not available
S-EPMC6850085 | biostudies-literature
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