Diabetes mellitus

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Unknown (27036)
Transcriptomics (1332)
Genomics (1303)
Proteomics (467)
Metabolomics (118)
Methylation profiling (38)
Genomic (36)
Models (31)
Clinical (29)
Other (21)
Multiomics (2)

Organisms

Homo sapiens (947)
Mus musculus (648)
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Danio rerio (11)
Drosophila melanogaster (7)
Caenorhabditis elegans (5)
cellular organisms (3)
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Actinoplanes sp. SE50/110 (2)
Arabidopsis thaliana (2)
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mouse gut metagenome (1)
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Gallus gallus (1)
Saccharomyces cerevisiae (1)
Bos indicus (1)

Organisms

Homo sapiens (319)
Mus musculus (186)
Rattus norvegicus (48)
human gut metagenome (17)
mouse gut metagenome (8)
feces metagenome (5)
Danio rerio (5)
unidentified (3)
human feces metagenome (3)
gut metagenome (3)
Meriones unguiculatus (2)
Felis catus (2)
Staphylococcus aureus (2)
Momordica cymbalaria (1)
Kalanchoe pinnata (1)
Actinoplanes sichuanensis (1)
Gymnopleurus humanus (1)
Gymnema sylvestre (1)
Arcanobacterium haemolyticum (1)
Rhizopus arrhizus (1)
Actinoplanes sp. SE50/110 (1)
Nocardia farcinica (1)
organismal metagenomes (1)
Mus sp. (1)
Macaca fascicularis (1)
Mus musculus musculus (1)
human eye metagenome (1)
Burkholderia pseudomallei (1)
human metagenome (1)
Purpureocillium lilacinum (1)

Repository

biostudies-arrayexpress (1042)
ENA (954)
geo (478)
pride (307)
EGA (185)
MetaboLights (109)
MassIVE (84)
iProX (44)
dbGaP (36)
BioModels (31)
ExpressionAtlas (15)
jPOST (15)
NODE (14)
EVA (11)
PanoramaPublic (11)
GNPS (5)
GPMDB (3)
MetabolomicsWorkbench (3)
PAXDB (1)

Tissue

Cell culture (40)
Blood plasma (32)
Liver (30)
Blood serum (16)
Hepatocyte (15)
Kidney (14)
Pancreas (14)
Type B pancreatic cell (14)
Pancreatic islet (13)
Islet of Langerhans (12)
Saliva (11)
Heart (11)
Blood cell (9)
Epithelial cell (9)
Skeletal muscle (9)
Feces (8)
Brain (8)
Adipose tissue (7)
Blood (6)
Permanent cell line cell (6)
White adipose tissue (6)
Macrophage (5)
Pancreatic islet beta cell (5)
Pancreatic islet cell (5)
Retina (5)
Blood (2)
Pancreatic islet (2)
Liver (1)
Urine (1)
Cell line (1)

Disease

Type 2 diabetes mellitus (181)
Diabetes mellitus (50)
Type 1 diabetes mellitus (48)
Normal (24)
Type II diabetes mellitus (5)
Permanent neonatal diabetes mellitus (4)
Type I diabetes mellitus (2)
Fatty liver disease (2)
Pre-diabetic (2)
Pre diabetic (2)
Insulin resistance (1)
Type II diabetes mellitus and post-ischemic heart failure (1)
Non diabetic and post-ischemic heart failure (1)
Pre-diabetes control (1)
Normoglycemic control (1)
Polyuria (1)
Amyloidosis (1)
Familial combined hyperlipidemia (1)
Insulitis and diabetes (1)
Aggressive insulitis (1)
Nondiabetic (1)
Diabetes mellitus type 1 (1)
Replicate control (1)
Mild hyperglycemia (1)
Mild hyperglycemia, liver dysfunction, and renal glycosuria (1)
Sjogren's syndrome (1)
Controled disease patient (1)
Gestational diabetes mellitus (1)
Type 1 Diabetes Mellitus (1)
Disease controled patient (1)

Technology Type

Mass Spectrometry (309)
Shotgun proteomics (163)
Mass spectrometry (76)
Bottom-up proteomics (55)
Data-dependent acquisition (33)
Mass spectrometry assay (26)
Data-independent acquisition (26)
Top-down proteomics (25)
Illumina HiSeq 2000 (7)
NMR spectroscopy (7)
Affymetrix 500K, unknown (4)
ILLUMINA, Illumina HiSeq 2500 (3)
Illumina (3)
Unknown, Affymetrix 500K (3)
ESI (2)
ILLUMINA, Illumina Genome Analyzer IIx, Illumina HiSeq 2500 (1)
Illumina HumanCoreExome-12v1-0 (1)
Illumina, unknown (1)
Illumina 450K, Bisulfite-Seq (1)
ILLUMINA, Illumina HiSeq 2000, Illumina HiSeq 2500 (ILLUMINA) (1)
Illumina HiSeq 2500 (ILLUMINA), Illumina HiSeq 2000, Illumina HiSeq 2500, ILLUMINA (1)
HiSeq X Ten, ILLUMINA (1)
Infinium_370k - GenomeStudio (1)
ILLUMINA, Illumina HiSeq 2000 (1)
ZCall, Illumina HumanExome-12v1_A-GenCall (1)
Illumina HumanHap 550 (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Illumina HumanExome-12v1_A-GenCall, zCall, GenoSNP, - Illuminus (1)
NMR spectroscopy assay (1)
NMR (1)

Instrument Platform

Illumina NovaSeq 6000 (27)
Illumina HiSeq 2500 (16)
NextSeq 500 (11)
Illumina HiSeq 2000 (10)
Affymetrix Fluidics Station 400 (6)
Illumina HiSeq 4000 (6)
Agilent G2565AA and G2565BA Microarray Scanner (4)
Illumina iScan (2)
Illumina Genome Analyzer (2)
Illumina Genome Analyzer IIx (2)
Illumina Genome Analyzer II (2)
Illumina HiSeq 1000 (2)
BGISEQ-500 (2)
Illumina MiSeq (2)
NextSeq 550 (2)
Chromium Controller, 10x Genomics and Chromium X, 10x Genomics (1)
Chromium Controller, 10x Genomics and Chromium X, 10x Genomics (1)
Cell culture (1)
C1000 Touch PCR thermal cycler (Bio-Rad) (1)
10X Genomics Chromium Single Cell Kit (1)
Illumina iScan microarray scanner (1)
Bioanalyzer, nano-drop (1)
GeneChip® Rat Gene 2.1 ST 24-Array Plate (1)
GeneTitan® Multi-Channel (MC) Instrument (1)
10x genomic Chromium controller (1)
Wollenberger tongs (1)
PromethION (1)
Covaris (1)
Computer and Applied Biosystems 7500 Real Time PCR Systems thermal cycler (1)
Agilent Surescan High Resolution DNA microarray Scanner (1)

Publication Date

2025 (171)
2014 (162)
2015 (143)
2024 (141)
2022 (139)
2012 (136)
2026 (133)
2013 (130)
2010 (124)
2023 (118)
2016 (101)
2021 (98)
2011 (91)
2019 (77)
2020 (71)
2009 (65)
2018 (58)
2017 (57)
2008 (57)
2007 (35)
2006 (15)
2005 (13)
2004 (4)
2002 (1)

UNIPROT ID/AC

P01308 (13)
P06213 (6)
P35568 (5)
P14672 (4)
O60343 (3)
P42345 (3)
P62753 (2)
P42346 (2)
P35570 (2)
Q6R327 (2)
P01275 (2)
P10515 (2)
Q8N122 (2)
P18510 (2)
Q96G03 (2)
P54840 (2)
Q16822 (2)
Q15181 (2)
P17858 (2)
P35557 (2)
O75390 (2)
P11168 (2)
P16118 (2)
P05062 (2)
P00338 (2)
P07195 (2)
P09622 (2)
P07864 (2)
P04406 (2)
P01584 (2)

CHEBI ID

CHEBI:30769 (27)
CHEBI:17234 (23)
CHEBI:32816 (21)
CHEBI:16027 (18)
CHEBI:15846 (11)
CHEBI:4167 (9)
CHEBI:16908 (5)
CHEBI:36080 (4)
CHEBI:16905 (4)
CHEBI:15422 (4)
CHEBI:422 (3)
CHEBI:15946 (3)
CHEBI:30744 (3)
CHEBI:15346 (3)
CHEBI:15996 (3)
CHEBI:17552 (3)
CHEBI:16761 (3)
CHEBI:16526 (3)
CHEBI:16001 (3)
CHEBI:16108 (3)
CHEBI:29052 (3)
CHEBI:28087 (3)
CHEBI:15377 (3)
CHEBI:15351 (3)
CHEBI:15361 (3)
CHEBI:29108 (3)
CHEBI:52217 (2)
CHEBI:18357 (2)
CHEBI:44897 (2)
CHEBI:17138 (2)

Metabolite Name

Creatine (17)
Hypoxanthine (17)
L-Glutamine (15)
L-Tyrosine (15)
Phenylalanine (14)
Uracil (14)
Taurine (14)
L-Serine (14)
Alanine (13)
Thymine (13)
L-Threonine (13)
Adenine (13)
Uridine (13)
Lysine (12)
Valine (12)
AMP (12)
Glycine (12)
L-Histidine (12)
L-Arginine (12)
L-Tryptophan (12)
Uric acid (12)
Xanthine (12)
L-Isoleucine (12)
L-Phenylalanine (12)
Serine (11)
Tyrosine (11)
Threonine (11)
Creatinine (11)
Ornithine (11)
Isoleucine (11)

First Public Date

2024 (150)
2025 (122)
2026 (116)
2022 (112)
2023 (105)
2014 (67)
2021 (63)
2019 (55)
2020 (53)
2017 (32)
2015 (28)
2018 (22)
2013 (19)
2016 (10)

Modelling Approach

Ordinary differential equation model (30)
Logical model (1)

Study status

Recruiting (11)
Not yet recruiting (6)
Completed (5)
Active, not recruiting (4)
Not provided (3)

Lab affiliation

Biological Sciences Division, Pacific Northwest National Laboratory (4)
Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany (4)
The University of Sydney, Australia (4)
Department of Immunotechnology, Lund University (3)
Pacific Northwest National Laboratory (3)
Research Unit for Molecular Medicine, Department of Clinical Medicine, Aarhus University, Denmark (3)
University of Malaya (3)
Department of Biochemistry and Molecular Biology School of Medicine, Oregon Health & Science University 3181 SW Sam Jackson Park Road Portland, OR 97239, USA (2)
Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (2)
Inserm U1016, Institut Cochin, 24 rue du Faubourg Saint-Jacques, 75014 PARIS, FRANCE. (2)
Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf, Auf´m Hennekamp 65, 40225 Düsseldorf, Germany (2)
Professor of biochemistry, deputy head of department Biomarker Research Group - group leader Department of Biochemistry and Molecular Biology Faculty of Medicine University of Debrecen 4032 Debrecen, Egyetem ter 1. (2)
Shiga University of Medical Science (2)
THE INSTITUTE OF BIOPHYSICS, CAS (2)
University of Bergen (2)
Wellcome Trust MRC Institute of Metabolic Science (2)
1 Health Management Center, the Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China; 2 Department of Cardiology, the Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China; (1)
1 IBMC-Institute for Molecular and Cell Biology, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal 2 ICBAS-School of Medicine and Biomedical Sciences, Universidade do Porto, Porto, Portugal (1)
1 Key Laboratory of Protein and Peptide Pharmaceuticals & Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China 2 University of Chinese Academy of Sciences, Beijing 100049, China (1)
1) Department Preclinical Development and Validation, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany; 2) Institute for Bioanalysis, University of Applied Science Coburg, Coburg, Germany (1)
1. Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany 2. Pediatric Neurology, University Hospital Essen, University of Duisburg-Essen, Faculty of Medicine, Essen, Germany (1)
1. iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal. 2. ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. Da República, 2780-157 Oeiras, Portugal. (1)
1Nutrient Metabolism & Signalling Laboratory, Metabolism, Diabetes and Obesity Program, Biomedicine Discovery Institute, Monash University, Victoria 3800, Australia. 2Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, Nursing & Health Sciences, Monash University, Victoria 3800, Australia. (1)
1Ruijin Yangtze River Delta Health Institute, Wuxi Branch of Ruijin Hospital, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (1)
4The Novo Nordisk Foundation Center for Protein Research, Clinical Proteomics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. (1)
AdventHealth von Weller Family Chair in Type 1 Diabetes Research Associate Investigator, Translational Research Institute (1)
Alitea Biotechnology GmbH (1)
Army Military Medical University (1)
Assoc. Prof. at Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark (1)
Associate Professor Pharmaceutical Sciences & Experimental Therapeutics College of Pharmacy FOE Diabetes Research Center University of Iowa (1)

Keyword

Diet (3)
Plant protein (2)
Animal protein (2)
Gut Hormones (1)
Bariatric Surgery (1)
Weight Loss Diets (1)
Anti-obesity Medications (1)
Endoscopic Metabolic and Bariatric Therapies (EMBT) (1)
Bariatric Endoscopy (1)
Intragastric balloon (IGB) (1)
Ablation Techniques (1)
Submucosal Tunneling Procedures (1)
Pylorus sparing antral myotomy (PSAM) (1)
Gastroplasty with endoscopic myotomy (GEM) (1)
Gastric peroral endoscopic myotomy (G-POEM) (1)
Tissue Plication (1)
Primary Obesity Surgery Endolumenal (POSE) (1)
Restorative Obesity Surgery Endoluminal (ROSE) (1)
Endoluminal sleeves (1)
Endoscopic Suturing (1)
Endoscopic Sleeve Gastroplasty (ESG) (1)
Laparoscopic adjustable gastric banding (LAGB) (1)
Laparoscopic sleeve gastrectomy (LSG) (1)
Roux-en-Y gastric bypass (RYGB) (1)
Bilio-pancreatic diversion (BPD) (1)
Bilio-pancreatic diversion with duodenal switch (BPD-DS) (1)
Pathophysiology of obesity (1)
RISK FACTOR (1)
Quality Measures, Social Determinants of Health (1)
Nutrition education (1)

IsPrivate

False (31)

Model Flag

Non Kinetic (3)

Classification

bacteria (7)
fungi (1)

Modification

Not available (2)

Study type

Transcription profiling by array (756)
RNA-seq of coding RNA (101)
Methylation profiling by array (43)
ChIP-seq (34)
RNA-seq of coding RNA from single cells (15)
RNA-seq of non coding RNA (10)
Transcription profiling by RT-PCR (9)
Unknown experiment type (8)
Methylation profiling by high throughput sequencing (8)
Other (6)
MicroRNA profiling by array (6)
Comparative genomic hybridization by array (5)
ChIP-chip by tiling array (4)
ChIP-chip by array (4)
Genotyping by array (4)
MicroRNA profiling by high throughput sequencing (3)
DNA-seq (3)
Proteomic profiling by array (3)
MeDIP-seq (2)
Bisulfite-seq (2)
RNA-seq of total RNA (2)
FAIRE-seq (1)
Transcription profiling by SAGE (1)
Cell line - Single-cell sequencing (1)
Metabolomic profiling (1)
Animal - One-color microarray (1)
Human - Methylation microarray (1)
Human - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)

Release Date

2022 (3812)
2025 (3310)
2023 (3212)
2021 (3042)
2024 (2745)
2020 (2318)
2019 (1752)
2018 (1461)
2017 (1185)
2016 (1085)
2015 (890)
2014 (757)
2013 (563)
2026 (443)
2012 (390)
2011 (291)
2010 (272)
2009 (193)
2008 (144)
2007 (66)
2006 (43)
2005 (25)
2004 (20)
2000 (16)
2003 (12)
2002 (7)
2001 (6)
1998 (5)
1997 (5)
1999 (2)

Location

United States (9)
China (4)
Canada (2)
Germany (2)
Finland (1)
India (1)
Taiwan (1)
Colombia (1)
Australia (1)
Belgium (1)
Brazil (1)

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Bilophila wadsworthia inhibits lifestyle intervention response in Gestational Diabetes Mellitus via L-glutamine regulation

Fecal samples were collected from 26 pregnant women with gestational diabetes mellitus (GDM) prior to and following a lifestyle intervention study, and subsequently analyzed using untargeted metabolomics.

2026-04-16 | MTBLS13807 | MetaboLights

EFO: In preparation - Early Metabolic Predictors of Type 2 Diabetes Mellitus in Normoglycemic Adults: Insights from Six-Year Prospective Cohort Study

INTRODUCTION: Type 2 Diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia, often preceded by latent metabolic disruptions. Early detection of metabolic alterations can facilitate timely intervention to delay or prevent T2DM onset. Metaboli...

2025-08-04 | MTBLS10965 | MetaboLights

Gut Microbiome and Serum Metabolic Alterations in Recurrent Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is a common complication of pregnancy, particularly affecting multiparous women with a history of GDM, who face a recurrence risk approaching 50%. This study investigates the association between gut microbiota modifications and metabolic profiles from early to ...

2025-07-21 | MTBLS12326 | MetaboLights

Omega-3 polyunsaturated fatty acids modulate gut microbiota-derived 18β-glycyrrhetinic acid to alleviate type 1 diabetes mellitus

Background

Omega-3 polyunsaturated fatty acids (PUFAs) are known to protect against type 1 diabetes mellitus (T1DM), but how they act through the gut-islet axis is not fully understood. This study explored how Omega-3 PUFA-influenced gut microbiota and their metabolites help protect pancrea...

2026-06-13 | MTBLS13006 | MetaboLights

Disorders of gut microbiota and fecal-serum metabolic patterns are associated with pulmonary tuberculosis and pulmonary tuberculosis co-morbid type 2 diabetes mellitus

BACKGROUND: Pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are prevalent chronic diseases with substantial implications for human health. DM patients are more susceptible to PTB, which exacerbates diabetes-related complications. However, the complex molecular mechanisms ...

2023-12-15 | MTBLS8729 | MetaboLights

Omega-3 polyunsaturated fatty acids modulate gut microbiota-derived 18β-glycyrrhetinic acid to alleviate type 1 diabetes mellitus

Background

2026-06-13 | MTBLS13174 | MetaboLights

Correlation of Candidate Genetic Variations for Susceptibility and Risk Assessment of Type 2 Diabetes Mellitus and its Related Medical Conditions among Filipinos (DM2)

Various studies have established the role of genetics in the development of type 2 diabetes mellitus (T2DM) across population groups with a reported heritability of 30–70%. These studies highlight the effect of interethnic variability in genetic susceptibility and risk for complications of T2DM. The...

ORGANISM(S): Homo sapiens

2026-09-01 | E-MTAB-17412 | biostudies-arrayexpress

Correlation of Candidate Genetic Variations for Susceptibility and Risk Assessment of Type 2 Diabetes Mellitus and its Related Medical Conditions among Filipinos (DM2)

ORGANISM(S): Homo sapiens

2026-09-01 | E-MTAB-17413 | biostudies-arrayexpress

Spatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

2025-11-26 | MTBLS12782 | MetaboLights

Integrated Multi-omics Analysis Identifies Diagnostic Biomarkers for Acute Coronary Syndrome in Type 2 Diabetes Mellitus Patients

Biomarkers for the early identification of acute coronary syndrome (ACS) risk remain inadequately investigated, particularly in patients with type 2 diabetes mellitus (T2DM), for whom timely clinical intervention may substantially enhance prognostic outcomes. The gut microbiota and serum metaboli...

2026-03-19 | MTBLS14087 | MetaboLights