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MetabolomicsGut Microbial Genes and Metabolism for Methionine and Branched-Chain Amino Acids in Diabetic Nephropathy

Diabetic mellitus nephropathy (DMN) is a serious complication of diabetes and a major health concern. Although the pathophysiology of diabetes mellitus (DM) leading to DMN is uncertain, recent evidence suggests the involvement of the gut microbiome. This study aimed to determine the relationships...

2023-03-01 | MTBLS6331 | MetaboLights
TranscriptomicsInteraction between diabetes and hypertension in a rat model of diabetic nephropathy
Fisher male Cyp1a1mRen2 rats were allocated into four groups of four biological replicates each: control; streptozotocin-induced diabetes alone; indole-3-carbinol induced hypertension alone; combined induced diabetes and hypertension.
Kidneys were harvested for microarray analysis.analysis.
ORGANISM(S): Rattus norvegicus 
2011-12-31 | E-MEXP-3165 | biostudies-arrayexpress
MetabolomicsPlasma metabolomic profiling of diabetic nephropathy in the steptozotocin induced type-1 diabetes mouse model
Not available
ORGANISM(S): Mus musculus 
ST000558 | MetabolomicsWorkbench
MetabolomicsKidney tissue metabolomic profiling of diabetic nephropathy in the steptozotocin induced type-1 diabetes mouse model.
Not available
ORGANISM(S): Mus musculus 
ST000540 | MetabolomicsWorkbench
TranscriptomicsGene expression profiling in glomeruli from human kidneys with diabetic nephropathy
Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy Keywords = Diabetes Keywords = kidney Keywords = glomeruli Keywords: other. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2004-04-01 | E-GEOD-1009 | biostudies-arrayexpress
TranscriptomicsDiabetes and hypertension then reversal in a rat model of diabetic nephropathy
Fisher male Cyp1a1mRen2 rats were allocated into three groups of four or eight biological replicates each: control; combined induced diabetes and hypertension; removal of combined treatments. Kidneys were harvested for gene expression microarray analysis on Affymetrix GeneChip Rat Genome 230 2.0 Gen...
ORGANISM(S): Rattus norvegicus 
2013-04-10 | E-MEXP-3739 | biostudies-arrayexpress
TranscriptomicsSystematic analysis of a human renal transcript dataset
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function. Quite a few of these genes show a specific or preferential mRNA expression in the renal glomerulus. To identify additional candidate genes ...
ORGANISM(S): Homo sapiens 
2010-07-19 | E-GEOD-21785 | biostudies-arrayexpress
MetabolomicsMetabolomics of diabetic nephropathy
Not available
ORGANISM(S): Homo sapiens 
ST000691 | MetabolomicsWorkbench
MetabolomicsDisorders of gut microbiota and fecal-serum metabolic patterns are associated with pulmonary tuberculosis and pulmonary tuberculosis co-morbid type 2 diabetes mellitus

BACKGROUND: Pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are prevalent chronic diseases with substantial implications for human health. DM patients are more susceptible to PTB, which exacerbates diabetes-related complications. However, the complex molecular mechanisms ...

2023-12-15 | MTBLS8729 | MetaboLights
MetabolomicsIntegration of metabolomics and transcriptomics reveals major metabolic pathways and potential biomarkers involved in pulmonary tuberculosis and pulmonary tuberculosis-complicated diabetes

Pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are common chronic diseases that threaten human health. Patients with DM are susceptible to PTB, an important factor that aggravates the complications of diabetes. However, the molecular regulatory mechanism underlying the susceptibility of ...

2023-07-26 | MTBLS7623 | MetaboLights
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