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Plants and microalgae have the ability to harness sunlight into energy dense molecules such as triacylglycerols (TAGs). TAGs hold great importance for human and animal nutrition, and are also a source for renewable energy. Acyl-CoA-dependent TAG synthesis by diacylglycerol acyltransferases (DGATs) i...
ORGANISM(S): Arabidopsis thaliana 
This study investigates lipid dysregulation in calcific aortic valve stenosis (CAVS) by analyzing lipid profiles in valve tissues from 99 patients across different disease severities (mild, moderate, severe) using liquid chromatography-mass spectrometry (LC-MS). The results reveal distinct lipid alt...
2025-01-28 | MTBLS11713 | MetaboLights

Lipid droplet (LD) growth mechanisms and the roles of LD-associated lipid transfer proteins remain poorly understood. Here, we show that the autophagy lipid transfer protein ATG2A has an anabolic role and promotes LD expansion by transferring diacylglycerol (DAG), and potentially triacylglycerol ...

2025-09-07 | MTBLS12951 | MetaboLights
Zebrafish are resilient to the loss of major diacylglycerol acyltransferase enzymes
Diacylglycerol Kinase Delta Improves Glucose Clearance and Protects Against the Development of Obesity
Lipid droplets impair anti-tumor immunity by disrupting IFNGR1 trafficking via TGN diacylglycerol depletion
mRNA-sequencing analysis of diacylglycerol kinase zeta overexpression MIN6 cells
Identification of diacylglycerol pyrophosphate regulated genes in ABA signaling.

The specific plant phosphorylated form of phosphatidic acid (PA), diacylglycerol pyrophosphate (DGPP) was recently shown to be a second messenger in abscisic acid (ABA) signaling. The aim of the project is to i...
ORGANISM(S): Arabidopsis thaliana 
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