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TranscriptomicsTranscriptional profiling of autophagy proficient and compromised cell lines, determined by expression levels of Atg5
Autophagy is activated in pancreatic ductal adenocarcinoma (PDAC) and is currently being considered a promising therapeutic target in clinical trials. PDAC is a highly lethal disease with incidence rate equalling mortality rate. Main reasons for PDAC lethality are late-stage diagnosis, high agressiv...
ORGANISM(S): Mus musculus 
2018-10-15 | E-MTAB-6275 | biostudies-arrayexpress
TranscriptomicsAutophagy_deficiency_pancreas
Transcriptional profiling analysis was performed on RNA from pancreatic tissue sections derived from autophagy deficient male mice at 4 and 18 weeks of age. Results were compared to littermate controls. Study groups contained RNA from pancreatic tissue sections of 1 control mouse and of 3 autophagy ...
ORGANISM(S): Mus musculus 
2015-04-07 | E-MTAB-2635 | biostudies-arrayexpress
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