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ProteomicsMudPIT analyses of the chromatin associated proteins isolated from the nucleus of Plasmodium falciparum at three time-points of the intraerythrocytic development cycle
Parasite cultures- Plasmodium falciparum strain 3D7 was cultured in human O+ erythrocytes at 5% hematocrit. Cultures were synchronized at ring stage with 5% (w/v) D-sorbitol treatments. Parasite cultures (8% parasitemia in 5% hematocrit) were harvested 48 hours after the first sorbitol treatment (ri...
ORGANISM(S): Plasmodium Falciparum 3d7 (ncbitaxon:36329) 
2018-06-28 | MSV000082520 | MassIVE
GenomicsAcetylated histone H3K56 interacts with Oct4 to promote mouse embryonic stem cell pluripotency
The presence of acetylated histone H3K56 in human embryonic stem cells (ESCs) correlates positively with the binding of Nanog, Sox2 and Oct4 (NSO) transcription factors at their target gene promoters. However, the function of H3K56ac there has been unclear. We now report that Oct4 interacts with K56...
ORGANISM(S): Mus musculus 
2013-06-25 | E-GEOD-47387 | biostudies-arrayexpress
TranscriptomicsThe alternative complement pathway appears to be a UVA sensor that leads to systemic immunosuppression
Ultraviolet (UV) wavebands in sunlight are immunomodulatory. About half the amount of UVA within a minimum erythemal dose of sunlight is systemically immunosuppressive, while higher doses protect from UVB immunosuppression in mice. We have previously shown that these responses to UVA are genetically...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15618 | biostudies-arrayexpress
TranscriptomicsThe transcription factor CDX2 maintains active enhancer in intestinal villus cells in vivo
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-34568 | biostudies-arrayexpress
ProteomicsMouse cerebellum lipidome response to West Nile Virus
Lipidomics data from mouse cerebellum; Treated with wild-type and mutant WNV, and mockulum
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-04-29 | MSV000081052 | MassIVE
ProteomicsMouse serum metabolome response to West Nile Virus (WNV)
Metabolomics data from mouse serum. Mice were inoculated with WNV-NY99 382.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-02-03 | MSV000091199 | MassIVE
GenomicsGenome-wide binding analysis of the transcriptional regulator TrmBL1 in Pyrococcus furiosus
The transcriptional regulator TrmBL1 from the hyperthermophilic euryarchaeon Pyrococcus furiosus functions as repressor as well as activator of genes encoding enzymes mainly involved in sugar uptake, glykolysis and gluconeogenesis. The aim of this study was to explore the genome-wide binding sites o...
ORGANISM(S): Pyrococcus furiosus DSM 3638 
2016-01-13 | E-MTAB-3959 | biostudies-arrayexpress
TranscriptomicsExpression profiling of S. pyogenes in response to Glucose and mutation of the regulators CcpA and LacD.1
Transcriptome changes were measured in S. pyogenes strain HSC5 in response to glucose availability, taking samples from the wild type strain (HSC5) grown in carbohydrate poor medium (C medium) versus this same medium with 1% (w/v) Glucose added. Furthermore, the effects of deletion of glucose respon...
ORGANISM(S): Streptococcus pyogenes 
2011-02-27 | E-GEOD-25253 | biostudies-arrayexpress
TranscriptomicsChIP-chip of Hmt1-9myc from S. cerevisiae
A comprehensive genome-wide binding profile for Hmt1 was obtained through the method of ChIP-chip using NimbleGen high-resolution tiling microarrays. Of the approximately 1000 Hmt1-binding sites found, the majority fall within or proximal to an ORF. However, Hmt1 occupancy is found at a number of ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-12-25 | E-GEOD-40505 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration
The Musashi-2 (Msi2) RNA-binding protein maintains stem cell self-renewal and promotes oncogenesis by enhancing cell proliferation in hematopoietic and gastrointestinal tissues. However, it is unclear how Msi2 recognizes and regulates mRNA targets in vivo and whether Msi2 primarily controls cell gro...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-71333 | biostudies-arrayexpress
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