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TranscriptomicsFetal Rat Testis mRNA Expression after 50 mg/kg Dibutyl Phthalate Exposure
High dose level dibutyl phthalate (DBP) exposure of fetal rat testes in vivo inhibits testosterone production (i.e. endocrine disruption). Here, fetal testis mRNA levels were profiled following exposure to a DBP dose level that did not significantly reduce testosterone levels. The goal was to iden...
ORGANISM(S): Rattus norvegicus 
2011-04-25 | E-GEOD-25196 | biostudies-arrayexpress
MetabolomicsPhyllosphere microbes mediate variety-specific accumulation of di-n-butyl phthalate in choysum (Brassica parachinensis)

Plant-microbe interactions in the phyllosphere have been demonstrated to facilitate plant growth and enhance resistance to diverse stresses; nevertheless, their role in the bioaccumulation of contaminants by plants is rarely considered. Here, by comparing differences in the phyllosphere morpholog...

2025-07-16 | MTBLS12464 | MetaboLights
TranscriptomicsIdentification of Rat foreskin biomarkers of in utero dibutyl phthalate exposure [Illumina]
Dibutyl phthalate was administered to pregnant Sprague Dawley rats from gestational days 16-20 at either a 100 mg/kg/day or 500 mg/kg/day dose level. This timeframe covers the reproductive masculinization window which corresponds to increased androgen signalling. Dibutyl phthalate has been shown t...
ORGANISM(S): Rattus norvegicus 
2013-07-12 | E-GEOD-48802 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of di-n-butyl phthalate and 17α ethinyl-oestradiol responses in three-spined stickleback testes
The data comes from a study, where three-spined sticklebacks (Gasterosteus aculeatus) were exposed to di-n-butyl phthalate (DBP) and 17α ethinyl-oestradiol (EE2) at nominal concentrations 35 μg/L and 40 ng/L, respectively, for four days. The aim of the study was to obtain insight into the acute tran...
ORGANISM(S): Gasterosteus aculeatus 
2015-10-10 | E-MTAB-3951 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of rat testis following combined fetal and postnatal DBP exposure
Provided later Pregnant Fisher 344 rats will be purchased from Charles River Laboratories, Inc. and delivered to CIIT on gestational day (GD) 7 (GD0 = day first vaginal plug positive). At gestational day 12 (GD12), the dams will be exposed once/day until GD20 to 50 mg/kg dibutyl phthalate (DBP) in ...
ORGANISM(S): Rattus norvegicus 
2008-11-24 | E-GEOD-13550 | biostudies-arrayexpress
TranscriptomicsPlastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations
Environmental compounds are known to promote epigenetic transgenerational inheritance of adult onset disease in subsequent generations (F1M-bM-^@M-^SF3) following ancestral exposure during fetal gonadal sex determination. The current study was designed to determine if a mixture of plastic derived en...
ORGANISM(S): Rattus norvegicus 
2014-07-22 | E-GEOD-59555 | biostudies-arrayexpress
TranscriptomicsIdentification of Rat foreskin biomarkers of in utero dibutyl phthalate exposure
Dibutyl phthalate was administered to pregnant Sprague Dawley rats from gestational days 16-20 at either a 100 mg/kg/day or 500 mg/kg/day dose level. This timeframe covers the reproductive masculinization window which corresponds to increased androgen signalling. Dibutyl phthalate has been shown t...
ORGANISM(S): Rattus norvegicus 
2013-06-04 | E-GEOD-47618 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testes following exposure to mono-(2-ethylhexyl) phthalate
In rodent models, phthalate exposure alters both the fetal and pubertal testis, but the resulting histopathological changes are divergent. This suggests that the underlying molecular and cellular phthalate mechanism may be age-dependent. Using genome-wide expression profiling of acutely-exposed ra...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4514 | biostudies-arrayexpress
TranscriptomicsIdentification of Rat foreskin biomarkers of in utero dibutyl phthalate exposure
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2013-07-12 | E-GEOD-48803 | biostudies-arrayexpress
ProteomicsFirst identification of a large set of serine hydrolases by activity-based protein profiling in dibutyl phthalate-exposed zebrafish larvae
Despite the involvement of several serine hydrolases (SHs) in the metabolism of xenobiotics such as dibutyl phthalate (DBP), no study has focused on mapping this enzyme class in zebrafish, a model organism frequently used in ecotoxicology. Here, we survey and identify active SHs in zebrafish larvae ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-03-11 | PXD038229 | Pride
Proteomics Zebrafish larvae Activity-based protein profiling Serine hydrolases Dibutyl phthalate 
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